| 1 | Sat 19 Aug | 182-1 v Plymouth ArgylePlymouth Argyle 1-2 Southampton |
| 2 | Sat 26 Aug | 182-1 v Queens Park RangersSouthampton 2-1 Queens Park Rangers |
| 3 | Sat 2 Sep | 18 0-5 v SunderlandSunderland 5-0 Southampton |
| 4 | Tue 19 Sep | 180-1 v Ipswich TownSouthampton 0-1 Ipswich Town |
| 5 | Tue 3 Oct | 181-0 v Stoke CityStoke City 0-1 Southampton |
| 6 | Sat 7 Oct | 181-1 v Rotherham UnitedSouthampton 1-1 Rotherham United |
| 7 | Sat 21 Oct | 182-1 v Hull CityHull City 1-2 Southampton |
| 8 | Wed 25 Oct | 182-2 v Preston North EndPreston North End 2-2 Southampton |
| 9 | Sat 2 Dec | 182-0 v Cardiff CitySouthampton 2-0 Cardiff City |
| 10 | Sat 9 Dec | 181-1 v WatfordWatford 1-1 Southampton |
| 11 | Wed 13 Dec | 181-1 v Coventry CityCoventry City 1-1 Southampton |
| 12 | Sat 16 Dec | 184-0 v Blackburn RoversSouthampton 4-0 Blackburn Rovers |
| 13 | Tue 26 Dec | 185-0 v Swansea CitySouthampton 5-0 Swansea City |
| 14 | Fri 29 Dec | 182-1 v Plymouth ArgyleSouthampton 2-1 Plymouth Argyle |
| 15 | Sat 13 Jan | 184-0 v Sheffield WednesdaySouthampton 4-0 Sheffield Wednesday |
| 16 | Sat 20 Jan | 183-1 v Swansea CitySwansea City 1-3 Southampton |
| 17 | Sat 3 Feb | 182-0 v Rotherham UnitedRotherham United 0-2 Southampton |
| 18 | Sat 10 Feb | 185-3 v Huddersfield TownSouthampton 5-3 Huddersfield Town |
| 19 | Tue 13 Feb | 181-3 v Bristol CityBristol City 3-1 Southampton |
| 20 | Fri 16 Feb | 182-0 v West Bromwich AlbionWest Bromwich Albion 0-2 Southampton |
| 21 | Tue 20 Feb | 181-2 v Hull CitySouthampton 1-2 Hull City |
| 22 | Sat 2 Mar | 184-3 v Birmingham CityBirmingham City 3-4 Southampton |
| 23 | Sat 9 Mar | 184-2 v SunderlandSouthampton 4-2 Sunderland |
| 24 | Fri 29 Mar | 181-1 v MiddlesbroughSouthampton 1-1 Middlesbrough |
| 25 | Sat 6 Apr | 180-0 v Blackburn RoversBlackburn Rovers 0-0 Southampton |
| 26 | Tue 9 Apr | 182-1 v Coventry CitySouthampton 2-1 Coventry City |
| 27 | Sat 13 Apr | 183-2 v WatfordSouthampton 3-2 Watford |
| 28 | Sat 27 Apr | 180-1 v Stoke CitySouthampton 0-1 Stoke City |
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