| 1 | Sat 12 Aug | 24 4-4 v Norwich CitySouthampton 4-4 Norwich City |
| 2 | Sat 19 Aug | 24 2-1 v Plymouth ArgylePlymouth Argyle 1-2 Southampton |
| 3 | Sat 26 Aug | 242-1 v Queens Park RangersSouthampton 2-1 Queens Park Rangers |
| 4 | Sat 2 Sep | 240-5 v SunderlandSunderland 5-0 Southampton |
| 5 | Fri 15 Sep | 241-4 v Leicester CitySouthampton 1-4 Leicester City |
| 6 | Tue 19 Sep | 240-1 v Ipswich TownSouthampton 0-1 Ipswich Town |
| 7 | Sat 23 Sep | 241-2 v MiddlesbroughMiddlesbrough 2-1 Southampton |
| 8 | Sat 30 Sep | 24 3-1 v Leeds UnitedSouthampton 3-1 Leeds United |
| 9 | Tue 3 Oct | 241-0 v Stoke CityStoke City 0-1 Southampton |
| 10 | Sat 21 Oct | 242-1 v Hull CityHull City 1-2 Southampton |
| 11 | Wed 25 Oct | 242-2 v Preston North EndPreston North End 2-2 Southampton |
| 12 | Sat 28 Oct | 243-1 v Birmingham CitySouthampton 3-1 Birmingham City |
| 13 | Sat 4 Nov | 241-0 v MillwallMillwall 0-1 Southampton |
| 14 | Sat 11 Nov | 242-1 v West Bromwich AlbionSouthampton 2-1 West Bromwich Albion |
| 15 | Sat 25 Nov | 241-1 v Huddersfield TownHuddersfield Town 1-1 Southampton |
| 16 | Wed 29 Nov | 241-0 v Bristol CitySouthampton 1-0 Bristol City |
| 17 | Sat 2 Dec | 242-0 v Cardiff CitySouthampton 2-0 Cardiff City |
| 18 | Sat 9 Dec | 24 1-1 v WatfordWatford 1-1 Southampton |
| 19 | Wed 13 Dec | 241-1 v Coventry CityCoventry City 1-1 Southampton |
| 20 | Sat 16 Dec | 244-0 v Blackburn RoversSouthampton 4-0 Blackburn Rovers |
| 21 | Sat 23 Dec | 24 1-0 v Queens Park RangersQueens Park Rangers 0-1 Southampton |
| 22 | Fri 29 Dec | 242-1 v Plymouth ArgyleSouthampton 2-1 Plymouth Argyle |
| 23 | Mon 1 Jan | 241-1 v Norwich CityNorwich City 1-1 Southampton |
| 24 | Sat 13 Jan | 244-0 v Sheffield WednesdaySouthampton 4-0 Sheffield Wednesday |
| 25 | Sat 20 Jan | 24 3-1 v Swansea CitySwansea City 1-3 Southampton |
| 26 | Sat 3 Feb | 242-0 v Rotherham UnitedRotherham United 0-2 Southampton |
| 27 | Tue 13 Feb | 241-3 v Bristol CityBristol City 3-1 Southampton |
| 28 | Fri 16 Feb | 242-0 v West Bromwich AlbionWest Bromwich Albion 0-2 Southampton |
| 29 | Tue 9 Apr | 242-1 v Coventry CitySouthampton 2-1 Coventry City |
| 30 | Tue 16 Apr | 243-0 v Preston North EndSouthampton 3-0 Preston North End |
| 31 | Tue 23 Apr | 240-5 v Leicester CityLeicester City 5-0 Southampton |
| 32 | Sat 27 Apr | 240-1 v Stoke CitySouthampton 0-1 Stoke City |
| 33 | Fri 17 May | 243-1 v West Bromwich AlbionSouthampton 3-1 West Bromwich Albion |
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