| 1 | Sun 15 Aug 2021 | 193-1 v Hertha Berlin1. FC Köln 3-1 Hertha Berlin | German Bundesliga |
| 2 | Sun 22 Aug 2021 | 192-3 v Bayern MunichBayern Munich 3-2 1. FC Köln | German Bundesliga |
| 3 | Sat 18 Sep 2021 | 191-1 v RB Leipzig1. FC Köln 1-1 RB Leipzig | German Bundesliga |
| 4 | Sat 25 Sep 2021 | 19 1-1 v Eintracht FrankfurtEintracht Frankfurt 1-1 1. FC Köln | German Bundesliga |
| 5 | Fri 1 Oct 2021 | 193-1 v Greuther Fürth1. FC Köln 3-1 Greuther Fürth | German Bundesliga |
| 6 | Fri 15 Oct 2021 | 190-5 v 1899 Hoffenheim1899 Hoffenheim 5-0 1. FC Köln | German Bundesliga |
| 7 | Sat 30 Oct 2021 | 190-2 v Borussia DortmundBorussia Dortmund 2-0 1. FC Köln | German Bundesliga |
| 8 | Sat 4 Dec 2021 | 191-1 v Arminia BielefeldArminia Bielefeld 1-1 1. FC Köln | German Bundesliga |
| 9 | Sat 15 Jan 2022 | 190-4 v Bayern Munich1. FC Köln 0-4 Bayern Munich | German Bundesliga |
| 10 | Sat 22 Jan 2022 | 192-2 v VfL BochumVfL Bochum 2-2 1. FC Köln | German Bundesliga |
| 11 | Sun 20 Mar 2022 | 191-1 v Borussia Dortmund1. FC Köln 1-1 Borussia Dortmund | German Bundesliga |
| 12 | Fri 1 Apr 2022 | 19 0-1 v 1. FC Union Berlin1. FC Union Berlin 1-0 1. FC Köln | German Bundesliga |
| 13 | Sat 9 Apr 2022 | 193-2 v Mainz 051. FC Köln 3-2 Mainz 05 | German Bundesliga |
| 14 | Sat 16 Apr 2022 | 193-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 1. FC Köln | German Bundesliga |
| 15 | Sat 23 Apr 2022 | 193-1 v Arminia Bielefeld1. FC Köln 3-1 Arminia Bielefeld | German Bundesliga |
| 16 | Sat 14 May 2022 | 191-2 v VfB StuttgartVfB Stuttgart 2-1 1. FC Köln | German Bundesliga |
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