| 1 | Sun 22 Aug 2021 | 252-3 v Bayern MunichBayern Munich 3-2 1. FC Köln | German Bundesliga |
| 2 | Sat 28 Aug 2021 | 252-1 v VfL Bochum1. FC Köln 2-1 VfL Bochum | German Bundesliga |
| 3 | Sat 11 Sep 2021 | 251-1 v SC FreiburgSC Freiburg 1-1 1. FC Köln | German Bundesliga |
| 4 | Fri 15 Oct 2021 | 250-5 v 1899 Hoffenheim1899 Hoffenheim 5-0 1. FC Köln | German Bundesliga |
| 5 | Fri 11 Feb 2022 | 251-3 v RB LeipzigRB Leipzig 3-1 1. FC Köln | German Bundesliga |
| 6 | Sun 6 Mar 2022 | 250-1 v 1899 Hoffenheim1. FC Köln 0-1 1899 Hoffenheim | German Bundesliga |
| 7 | Sun 13 Mar 2022 | 251-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-1 1. FC Köln | German Bundesliga |
| 8 | Fri 1 Apr 2022 | 250-1 v 1. FC Union Berlin1. FC Union Berlin 1-0 1. FC Köln | German Bundesliga |
| 9 | Sat 9 Apr 2022 | 253-2 v Mainz 051. FC Köln 3-2 Mainz 05 | German Bundesliga |
| 10 | Sat 16 Apr 2022 | 253-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 1. FC Köln | German Bundesliga |
| 11 | Sat 30 Apr 2022 | 254-1 v FC AugsburgFC Augsburg 1-4 1. FC Köln | German Bundesliga |
| 12 | Sat 7 May 2022 | 250-1 v VfL Wolfsburg1. FC Köln 0-1 VfL Wolfsburg | German Bundesliga |
| 13 | Sat 14 May 2022 | 251-2 v VfB StuttgartVfB Stuttgart 2-1 1. FC Köln | German Bundesliga |
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