| 1 | Sat 17 Oct 2020 | 170-1 v Borussia Dortmund1899 Hoffenheim 0-1 Borussia Dortmund | German Bundesliga |
| 2 | Thu 22 Oct 2020 | 172-0 v Red Star Belgrade1899 Hoffenheim 2-0 Red Star Belgrade | Europa League Group L |
| 3 | Sun 25 Oct 2020 | 171-1 v Werder BremenWerder Bremen 1-1 1899 Hoffenheim | German Bundesliga |
| 4 | Thu 29 Oct 2020 | 174-1 v KAA GentKAA Gent 1-4 1899 Hoffenheim | Europa League Group L |
| 5 | Mon 2 Nov 2020 | 171-3 v 1. FC Union Berlin1899 Hoffenheim 1-3 1. FC Union Berlin | German Bundesliga |
| 6 | Sun 8 Nov 2020 | 171-2 v VfL WolfsburgVfL Wolfsburg 2-1 1899 Hoffenheim | German Bundesliga |
| 7 | Sat 21 Nov 2020 | 17 3-3 v VfB Stuttgart1899 Hoffenheim 3-3 VfB Stuttgart | German Bundesliga |
| 8 | Thu 26 Nov 2020 | 172-0 v Slovan LiberecSlovan Liberec 0-2 1899 Hoffenheim | Europa League Group L |
| 9 | Sun 29 Nov 2020 | 171-1 v Mainz 05Mainz 05 1-1 1899 Hoffenheim | German Bundesliga |
| 10 | Thu 3 Dec 2020 | 170-0 v Red Star BelgradeRed Star Belgrade 0-0 1899 Hoffenheim | Europa League Group L |
| 11 | Mon 7 Dec 2020 | 173-1 v FC Augsburg1899 Hoffenheim 3-1 FC Augsburg | German Bundesliga |
| 12 | Sun 13 Dec 2020 | 171-4 v Bayer 04 LeverkusenBayer 04 Leverkusen 4-1 1899 Hoffenheim | German Bundesliga |
| 13 | Wed 16 Dec 2020 | 17 0-1 v RB Leipzig1899 Hoffenheim 0-1 RB Leipzig | German Bundesliga |
| 14 | Sat 19 Dec 2020 | 172-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-2 1899 Hoffenheim | German Bundesliga |
| 15 | Sat 2 Jan 2021 | 171-3 v SC Freiburg1899 Hoffenheim 1-3 SC Freiburg | German Bundesliga |
| 16 | Sun 21 Feb 2021 | 174-0 v Werder Bremen1899 Hoffenheim 4-0 Werder Bremen | German Bundesliga |
| 17 | Thu 25 Feb 2021 | 170-2 v Molde1899 Hoffenheim 0-2 Molde | Europa League Round of 32 |
| 18 | Sun 28 Feb 2021 | 171-1 v 1. FC Union Berlin1. FC Union Berlin 1-1 1899 Hoffenheim | German Bundesliga |
| 19 | Sat 6 Mar 2021 | 17 2-1 v VfL Wolfsburg1899 Hoffenheim 2-1 VfL Wolfsburg | German Bundesliga |
| 20 | Sun 14 Mar 2021 | 17 0-2 v VfB StuttgartVfB Stuttgart 2-0 1899 Hoffenheim | German Bundesliga |
| 21 | Sat 3 Apr 2021 | 171-2 v FC AugsburgFC Augsburg 2-1 1899 Hoffenheim | German Bundesliga |
| 22 | Mon 12 Apr 2021 | 170-0 v Bayer 04 Leverkusen1899 Hoffenheim 0-0 Bayer 04 Leverkusen | German Bundesliga |
| 23 | Fri 16 Apr 2021 | 170-0 v RB LeipzigRB Leipzig 0-0 1899 Hoffenheim | German Bundesliga |
| 24 | Wed 21 Apr 2021 | 173-2 v Borussia Mönchengladbach1899 Hoffenheim 3-2 Borussia Mönchengladbach | German Bundesliga |
| 25 | Sat 24 Apr 2021 | 171-1 v SC FreiburgSC Freiburg 1-1 1899 Hoffenheim | German Bundesliga |
| 26 | Sat 8 May 2021 | 174-2 v FC Schalke 041899 Hoffenheim 4-2 FC Schalke 04 | German Bundesliga |
| 27 | Sat 15 May 2021 | 171-1 v Arminia BielefeldArminia Bielefeld 1-1 1899 Hoffenheim | German Bundesliga |
| 28 | Sat 22 May 2021 | 172-1 v Hertha Berlin1899 Hoffenheim 2-1 Hertha Berlin | German Bundesliga |
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