| 1 | Sat 31 Jul 2021 | 55-0 v Milton Keynes DonsAFC Bournemouth 5-0 Milton Keynes Dons | Carabao Cup First Round |
| 2 | Fri 6 Aug 2021 | 52-2 v West Bromwich AlbionAFC Bournemouth 2-2 West Bromwich Albion | Sky Bet Championship |
| 3 | Sat 14 Aug 2021 | 52-1 v Nottingham ForestNottingham Forest 1-2 AFC Bournemouth | Sky Bet Championship |
| 4 | Wed 18 Aug 2021 | 52-0 v Birmingham CityBirmingham City 0-2 AFC Bournemouth | Sky Bet Championship |
| 5 | Sat 21 Aug 2021 | 52-2 v BlackpoolAFC Bournemouth 2-2 Blackpool | Sky Bet Championship |
| 6 | Sat 28 Aug 2021 | 50-0 v Hull CityHull City 0-0 AFC Bournemouth | Sky Bet Championship |
| 7 | Sat 11 Sep 2021 | 5 3-0 v BarnsleyAFC Bournemouth 3-0 Barnsley | Sky Bet Championship |
| 8 | Tue 14 Sep 2021 | 5 2-1 v Queens Park RangersAFC Bournemouth 2-1 Queens Park Rangers | Sky Bet Championship |
| 9 | Sat 18 Sep 2021 | 51-0 v Cardiff CityCardiff City 0-1 AFC Bournemouth | Sky Bet Championship |
| 10 | Sat 25 Sep 2021 | 52-1 v Luton TownAFC Bournemouth 2-1 Luton Town | Sky Bet Championship |
| 11 | Wed 29 Sep 2021 | 50-0 v Peterborough UnitedPeterborough United 0-0 AFC Bournemouth | Sky Bet Championship |
| 12 | Sat 2 Oct 2021 | 52-1 v Sheffield UnitedAFC Bournemouth 2-1 Sheffield United | Sky Bet Championship |
| 13 | Sat 16 Oct 2021 | 5 2-0 v Bristol CityBristol City 0-2 AFC Bournemouth | Sky Bet Championship |
| 14 | Sat 23 Oct 2021 | 53-0 v Huddersfield TownAFC Bournemouth 3-0 Huddersfield Town | Sky Bet Championship |
| 15 | Sat 30 Oct 2021 | 52-0 v ReadingReading 0-2 AFC Bournemouth | Sky Bet Championship |
| 16 | Wed 3 Nov 2021 | 51-2 v Preston North EndAFC Bournemouth 1-2 Preston North End | Sky Bet Championship |
| 17 | Sat 6 Nov 2021 | 54-0 v Swansea CityAFC Bournemouth 4-0 Swansea City | Sky Bet Championship |
| 18 | Sat 11 Dec 2021 | 50-2 v Blackburn RoversAFC Bournemouth 0-2 Blackburn Rovers | Sky Bet Championship |
| 19 | Sat 18 Dec 2021 | 50-1 v MiddlesbroughMiddlesbrough 1-0 AFC Bournemouth | Sky Bet Championship |
| 20 | Thu 30 Dec 2021 | 53-0 v Cardiff CityAFC Bournemouth 3-0 Cardiff City | Sky Bet Championship |
| 21 | Sat 15 Jan 2022 | 52-3 v Luton TownLuton Town 3-2 AFC Bournemouth | Sky Bet Championship |
| 22 | Sat 22 Jan 2022 | 50-1 v Hull CityAFC Bournemouth 0-1 Hull City | Sky Bet Championship |
| 23 | Sat 29 Jan 2022 | 51-0 v BarnsleyBarnsley 0-1 AFC Bournemouth | Sky Bet Championship |
| 24 | Wed 9 Feb 2022 | 53-1 v Birmingham CityAFC Bournemouth 3-1 Birmingham City | Sky Bet Championship |
| 25 | Sat 12 Feb 2022 | 52-1 v BlackpoolBlackpool 1-2 AFC Bournemouth | Sky Bet Championship |
| 26 | Sat 26 Feb 2022 | 5 2-1 v Stoke CityAFC Bournemouth 2-1 Stoke City | Sky Bet Championship |
| 27 | Sat 5 Mar 2022 | 51-2 v Preston North EndPreston North End 2-1 AFC Bournemouth | Sky Bet Championship |
| 28 | Tue 8 Mar 2022 | 51-1 v Peterborough UnitedAFC Bournemouth 1-1 Peterborough United | Sky Bet Championship |
| 29 | Sat 12 Mar 2022 | 52-0 v Derby CountyAFC Bournemouth 2-0 Derby County | Sky Bet Championship |
| 30 | Tue 15 Mar 2022 | 51-1 v ReadingAFC Bournemouth 1-1 Reading | Sky Bet Championship |
| 31 | Sat 19 Mar 2022 | 53-0 v Huddersfield TownHuddersfield Town 0-3 AFC Bournemouth | Sky Bet Championship |
| 32 | Sat 2 Apr 2022 | 53-2 v Bristol CityAFC Bournemouth 3-2 Bristol City | Sky Bet Championship |
| 33 | Wed 6 Apr 2022 | 5 0-2 v West Bromwich AlbionWest Bromwich Albion 2-0 AFC Bournemouth | Sky Bet Championship |
| 34 | Sat 9 Apr 2022 | 5 0-0 v Sheffield UnitedSheffield United 0-0 AFC Bournemouth | Sky Bet Championship |
| 35 | Fri 15 Apr 2022 | 50-0 v MiddlesbroughAFC Bournemouth 0-0 Middlesbrough | Sky Bet Championship |
| 36 | Mon 18 Apr 2022 | 53-0 v Coventry CityCoventry City 0-3 AFC Bournemouth | Sky Bet Championship |
| 37 | Sat 23 Apr 2022 | 51-1 v FulhamAFC Bournemouth 1-1 Fulham | Sky Bet Championship |
| 38 | Tue 26 Apr 2022 | 53-3 v Swansea CitySwansea City 3-3 AFC Bournemouth | Sky Bet Championship |
| 39 | Sat 30 Apr 2022 | 53-0 v Blackburn RoversBlackburn Rovers 0-3 AFC Bournemouth | Sky Bet Championship |
| 40 | Tue 3 May 2022 | 51-0 v Nottingham ForestAFC Bournemouth 1-0 Nottingham Forest | Sky Bet Championship |
| 41 | Sat 7 May 2022 | 51-0 v MillwallAFC Bournemouth 1-0 Millwall | Sky Bet Championship |
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