| 1 | Sun 6 Aug | 41-1 v Manchester CityManchester City 1-1 Arsenal | Community Shield Final |
| 2 | Sat 12 Aug | 4 2-1 v Nottingham ForestArsenal 2-1 Nottingham Forest | Premier League |
| 3 | Mon 21 Aug | 41-0 v Crystal PalaceCrystal Palace 0-1 Arsenal | Premier League |
| 4 | Sat 26 Aug | 42-2 v FulhamArsenal 2-2 Fulham | Premier League |
| 5 | Sun 3 Sep | 43-1 v Manchester UnitedArsenal 3-1 Manchester United | Premier League |
| 6 | Sun 17 Sep | 41-0 v EvertonEverton 0-1 Arsenal | Premier League |
| 7 | Wed 20 Sep | 4 4-0 v PSV EindhovenArsenal 4-0 PSV Eindhoven | UEFA Champions League Group B |
| 8 | Sun 24 Sep | 42-2 v Tottenham HotspurArsenal 2-2 Tottenham Hotspur | Premier League |
| 9 | Wed 27 Sep | 4 1-0 v BrentfordBrentford 0-1 Arsenal | Carabao Cup Third Round |
| 10 | Sat 30 Sep | 44-0 v AFC BournemouthAFC Bournemouth 0-4 Arsenal | Premier League |
| 11 | Tue 3 Oct | 41-2 v LensLens 2-1 Arsenal | UEFA Champions League Group B |
| 12 | Sun 8 Oct | 41-0 v Manchester CityArsenal 1-0 Manchester City | Premier League |
| 13 | Sat 21 Oct | 4 2-2 v ChelseaChelsea 2-2 Arsenal | Premier League |
| 14 | Tue 24 Oct | 42-1 v SevillaSevilla 1-2 Arsenal | UEFA Champions League Group B |
| 15 | Sat 28 Oct | 45-0 v Sheffield UnitedArsenal 5-0 Sheffield United | Premier League |
| 16 | Wed 1 Nov | 41-3 v West Ham UnitedWest Ham United 3-1 Arsenal | Carabao Cup Fourth Round |
| 17 | Sat 4 Nov | 40-1 v Newcastle UnitedNewcastle United 1-0 Arsenal | Premier League |
| 18 | Wed 8 Nov | 42-0 v SevillaArsenal 2-0 Sevilla | UEFA Champions League Group B |
| 19 | Sat 25 Nov | 41-0 v BrentfordBrentford 0-1 Arsenal | Premier League |
| 20 | Wed 29 Nov | 46-0 v LensArsenal 6-0 Lens | UEFA Champions League Group B |
| 21 | Sat 2 Dec | 42-1 v Wolverhampton WanderersArsenal 2-1 Wolverhampton Wanderers | Premier League |
| 22 | Tue 5 Dec | 44-3 v Luton TownLuton Town 3-4 Arsenal | Premier League |
| 23 | Sat 9 Dec | 40-1 v Aston VillaAston Villa 1-0 Arsenal | Premier League |
| 24 | Tue 12 Dec | 41-1 v PSV EindhovenPSV Eindhoven 1-1 Arsenal | UEFA Champions League Group B |
| 25 | Sun 17 Dec | 4 2-0 v Brighton & Hove AlbionArsenal 2-0 Brighton & Hove Albion | Premier League |
| 26 | Sat 23 Dec | 4 1-1 v LiverpoolLiverpool 1-1 Arsenal | Premier League |
| 27 | Thu 28 Dec | 40-2 v West Ham UnitedArsenal 0-2 West Ham United | Premier League |
| 28 | Sun 31 Dec | 41-2 v FulhamFulham 2-1 Arsenal | Premier League |
| 29 | Sun 7 Jan | 40-2 v LiverpoolArsenal 0-2 Liverpool | Emirates FA Cup Third Round |
| 30 | Sat 20 Jan | 45-0 v Crystal PalaceArsenal 5-0 Crystal Palace | Premier League |
| 31 | Tue 30 Jan | 42-1 v Nottingham ForestNottingham Forest 1-2 Arsenal | Premier League |
| 32 | Sun 4 Feb | 4 3-1 v LiverpoolArsenal 3-1 Liverpool | Premier League |
| 33 | Sun 11 Feb | 46-0 v West Ham UnitedWest Ham United 0-6 Arsenal | Premier League |
| 34 | Sat 17 Feb | 45-0 v BurnleyBurnley 0-5 Arsenal | Premier League |
| 35 | Wed 21 Feb | 40-1 v FC PortoFC Porto 1-0 Arsenal | UEFA Champions League Round of 16 |
| 36 | Sat 24 Feb | 44-1 v Newcastle UnitedArsenal 4-1 Newcastle United | Premier League |
| 37 | Mon 4 Mar | 46-0 v Sheffield UnitedSheffield United 0-6 Arsenal | Premier League |
| 38 | Sat 9 Mar | 42-1 v BrentfordArsenal 2-1 Brentford | Premier League |
| 39 | Tue 12 Mar | 41-0 v FC PortoArsenal 1-0 FC Porto | UEFA Champions League Round of 16 |
| 40 | Sun 31 Mar | 40-0 v Manchester CityManchester City 0-0 Arsenal | Premier League |
| 41 | Wed 3 Apr | 42-0 v Luton TownArsenal 2-0 Luton Town | Premier League |
| 42 | Sat 6 Apr | 4 3-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-3 Arsenal | Premier League |
| 43 | Tue 9 Apr | 42-2 v Bayern MunichArsenal 2-2 Bayern Munich | UEFA Champions League Quarter Final |
| 44 | Sun 14 Apr | 4 0-2 v Aston VillaArsenal 0-2 Aston Villa | Premier League |
| 45 | Wed 17 Apr | 4 0-1 v Bayern MunichBayern Munich 1-0 Arsenal | UEFA Champions League Quarter Final |
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