| 1 | Sat 25 Mar | 213-0 v NorwaySpain 3-0 Norway | European Championship Qualification Group A |
| 2 | Sat 19 Aug | 72-3 v Bayer 04 LeverkusenBayer 04 Leverkusen 3-2 RB Leipzig | German Bundesliga |
| 3 | Fri 25 Aug | 75-1 v VfB StuttgartRB Leipzig 5-1 VfB Stuttgart | German Bundesliga |
| 4 | Sun 3 Sep | 73-0 v 1 FC Union Berlin1 FC Union Berlin 0-3 RB Leipzig | German Bundesliga |
| 5 | Fri 8 Sep | 217-1 v GeorgiaGeorgia 1-7 Spain | European Championship Qualification Group A |
| 6 | Sat 21 Oct | 73-1 v Darmstadt 98Darmstadt 98 1-3 RB Leipzig | German Bundesliga |
| 7 | Wed 25 Oct | 73-1 v Red Star BelgradeRB Leipzig 3-1 Red Star Belgrade | UEFA Champions League Group G |
| 8 | Sat 28 Oct | 76-0 v 1 FC KölnRB Leipzig 6-0 1 FC Köln | German Bundesliga |
| 9 | Sat 13 Jan | 70-1 v Eintracht FrankfurtRB Leipzig 0-1 Eintracht Frankfurt | German Bundesliga |
| 10 | Sat 20 Jan | 72-3 v Bayer 04 LeverkusenRB Leipzig 2-3 Bayer 04 Leverkusen | German Bundesliga |
| 11 | Sat 27 Jan | 72-5 v VfB StuttgartVfB Stuttgart 5-2 RB Leipzig | German Bundesliga |
| 12 | Sun 4 Feb | 72-0 v 1 FC Union BerlinRB Leipzig 2-0 1 FC Union Berlin | German Bundesliga |
| 13 | Sat 10 Feb | 72-2 v FC AugsburgFC Augsburg 2-2 RB Leipzig | German Bundesliga |
| 14 | Tue 13 Feb | 70-1 v Real MadridRB Leipzig 0-1 Real Madrid | UEFA Champions League Round of 16 |
| 15 | Sat 17 Feb | 72-0 v Borussia MönchengladbachRB Leipzig 2-0 Borussia Mönchengladbach | German Bundesliga |
| 16 | Sat 24 Feb | 71-2 v Bayern MunichBayern Munich 2-1 RB Leipzig | German Bundesliga |
| 17 | Sat 2 Mar | 74-1 v VfL BochumVfL Bochum 1-4 RB Leipzig | German Bundesliga |
| 18 | Wed 6 Mar | 71-1 v Real MadridReal Madrid 1-1 RB Leipzig | UEFA Champions League Round of 16 |
| 19 | Sat 9 Mar | 72-0 v Darmstadt 98RB Leipzig 2-0 Darmstadt 98 | German Bundesliga |
| 20 | Fri 15 Mar | 75-1 v 1 FC Köln1 FC Köln 1-5 RB Leipzig | German Bundesliga |
| 21 | Tue 26 Mar | 103-3 v BrazilSpain 3-3 Brazil | International Friendly |
| 22 | Sat 30 Mar | 70-0 v Mainz 05RB Leipzig 0-0 Mainz 05 | German Bundesliga |
| 23 | Sat 6 Apr | 74-1 v SC FreiburgSC Freiburg 1-4 RB Leipzig | German Bundesliga |
| 24 | Sat 13 Apr | 73-0 v VfL WolfsburgRB Leipzig 3-0 VfL Wolfsburg | German Bundesliga |
| 25 | Sat 20 Apr | 72-1 v 1 FC Heidenheim1 FC Heidenheim 1-2 RB Leipzig | German Bundesliga |
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