| 1 | Sat 16 Sep | 274-0 v NEC NijmegenPSV Eindhoven 4-0 NEC Nijmegen | Dutch Eredivisie |
| 2 | Wed 20 Sep | 270-4 v ArsenalArsenal 4-0 PSV Eindhoven | UEFA Champions League Group B |
| 3 | Sat 23 Sep | 274-0 v Almere CityAlmere City 0-4 PSV Eindhoven | Dutch Eredivisie |
| 4 | Wed 27 Sep | 273-0 v Go Ahead EaglesPSV Eindhoven 3-0 Go Ahead Eagles | Dutch Eredivisie |
| 5 | Tue 3 Oct | 27 2-2 v SevillaPSV Eindhoven 2-2 Sevilla | UEFA Champions League Group B |
| 6 | Sun 8 Oct | 274-0 v Sparta RotterdamSparta Rotterdam 0-4 PSV Eindhoven | Dutch Eredivisie |
| 7 | Sun 15 Oct | 222-0 v GhanaMexico 2-0 Ghana | International Friendly |
| 8 | Wed 18 Oct | 222-2 v GermanyMexico 2-2 Germany | International Friendly |
| 9 | Sat 21 Oct | 273-1 v Fortuna SittardPSV Eindhoven 3-1 Fortuna Sittard | Dutch Eredivisie |
| 10 | Tue 24 Oct | 271-1 v LensLens 1-1 PSV Eindhoven | UEFA Champions League Group B |
| 11 | Sun 29 Oct | 275-2 v AjaxPSV Eindhoven 5-2 Ajax | Dutch Eredivisie |
| 12 | Sat 4 Nov | 276-0 v Heracles AlmeloHeracles Almelo 0-6 PSV Eindhoven | Dutch Eredivisie |
| 13 | Wed 8 Nov | 27 1-0 v LensPSV Eindhoven 1-0 Lens | UEFA Champions League Group B |
| 14 | Sun 12 Nov | 274-0 v PEC ZwollePSV Eindhoven 4-0 PEC Zwolle | Dutch Eredivisie |
| 15 | Sat 25 Nov | 273-0 v FC TwenteFC Twente 0-3 PSV Eindhoven | Dutch Eredivisie |
| 16 | Wed 29 Nov | 27 3-2 v SevillaSevilla 2-3 PSV Eindhoven | UEFA Champions League Group B |
| 17 | Sun 21 Jan | 271-1 v FC UtrechtFC Utrecht 1-1 PSV Eindhoven | Dutch Eredivisie |
| 18 | Sat 27 Jan | 272-0 v Almere CityPSV Eindhoven 2-0 Almere City | Dutch Eredivisie |
| 19 | Sat 3 Feb | 27 1-1 v AjaxAjax 1-1 PSV Eindhoven | Dutch Eredivisie |
| 20 | Sun 11 Feb | 275-1 v VolendamVolendam 1-5 PSV Eindhoven | Dutch Eredivisie |
| 21 | Fri 16 Feb | 272-0 v Heracles AlmeloPSV Eindhoven 2-0 Heracles Almelo | Dutch Eredivisie |
| 22 | Tue 20 Feb | 27 1-1 v Borussia DortmundPSV Eindhoven 1-1 Borussia Dortmund | UEFA Champions League Round of 16 |
| 23 | Sat 24 Feb | 277-1 v PEC ZwollePEC Zwolle 1-7 PSV Eindhoven | Dutch Eredivisie |
| 24 | Sun 3 Mar | 27 2-2 v FeyenoordPSV Eindhoven 2-2 Feyenoord | Dutch Eredivisie |
| 25 | Fri 8 Mar | 271-0 v Go Ahead EaglesGo Ahead Eagles 0-1 PSV Eindhoven | Dutch Eredivisie |
| 26 | Wed 13 Mar | 270-2 v Borussia DortmundBorussia Dortmund 2-0 PSV Eindhoven | UEFA Champions League Round of 16 |
| 27 | Sun 17 Mar | 271-0 v FC TwentePSV Eindhoven 1-0 FC Twente | Dutch Eredivisie |
| 28 | Sat 30 Mar | 271-3 v NEC NijmegenNEC Nijmegen 3-1 PSV Eindhoven | Dutch Eredivisie |
| 29 | Sat 13 Apr | 276-0 v VitessePSV Eindhoven 6-0 Vitesse | Dutch Eredivisie |
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