| 1 | Sun 13 Aug | 222-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 2 | Sun 20 Aug | 22 0-0 v Atlético MadridReal Betis 0-0 Atlético Madrid | Spanish La Liga |
| 3 | Sun 27 Aug | 222-4 v Athletic BilbaoAthletic Bilbao 4-2 Real Betis | Spanish La Liga |
| 4 | Sat 2 Sep | 221-0 v Rayo VallecanoReal Betis 1-0 Rayo Vallecano | Spanish La Liga |
| 5 | Sat 16 Sep | 220-5 v BarcelonaBarcelona 5-0 Real Betis | Spanish La Liga |
| 6 | Thu 21 Sep | 220-1 v RangersRangers 1-0 Real Betis | UEFA Europa League Group C |
| 7 | Sun 24 Sep | 22 1-1 v CádizReal Betis 1-1 Cádiz | Spanish La Liga |
| 8 | Thu 28 Sep | 221-1 v GranadaGranada 1-1 Real Betis | Spanish La Liga |
| 9 | Sun 1 Oct | 223-0 v ValenciaReal Betis 3-0 Valencia | Spanish La Liga |
| 10 | Thu 5 Oct | 222-1 v Sparta PragueReal Betis 2-1 Sparta Prague | UEFA Europa League Group C |
| 11 | Sun 8 Oct | 22 1-1 v AlavésAlavés 1-1 Real Betis | Spanish La Liga |
| 12 | Sat 21 Oct | 221-1 v GetafeGetafe 1-1 Real Betis | Spanish La Liga |
| 13 | Thu 26 Oct | 221-0 v Aris LimassolAris Limassol 0-1 Real Betis | UEFA Europa League Group C |
| 14 | Sun 29 Oct | 22 2-1 v OsasunaReal Betis 2-1 Osasuna | Spanish La Liga |
| 15 | Sat 4 Nov | 222-0 v MallorcaReal Betis 2-0 Mallorca | Spanish La Liga |
| 16 | Thu 9 Nov | 224-1 v Aris LimassolReal Betis 4-1 Aris Limassol | UEFA Europa League Group C |
| 17 | Sun 12 Nov | 221-1 v SevillaSevilla 1-1 Real Betis | Spanish La Liga |
| 18 | Sun 26 Nov | 221-0 v Las PalmasReal Betis 1-0 Las Palmas | Spanish La Liga |
| 19 | Thu 30 Nov | 220-1 v Sparta PragueSparta Prague 1-0 Real Betis | UEFA Europa League Group C |
| 20 | Sun 3 Dec | 220-0 v AlmeríaAlmería 0-0 Real Betis | Spanish La Liga |
| 21 | Sat 9 Dec | 221-1 v Real MadridReal Betis 1-1 Real Madrid | Spanish La Liga |
| 22 | Thu 14 Dec | 22 2-3 v RangersReal Betis 2-3 Rangers | UEFA Europa League Group C |
| 23 | Sun 17 Dec | 22 0-0 v Real SociedadReal Sociedad 0-0 Real Betis | Spanish La Liga |
| 24 | Wed 3 Jan | 221-2 v Celta VigoCelta Vigo 2-1 Real Betis | Spanish La Liga |
| 25 | Sat 13 Jan | 22 1-0 v GranadaReal Betis 1-0 Granada | Spanish La Liga |
| 26 | Sun 21 Jan | 222-4 v BarcelonaReal Betis 2-4 Barcelona | Spanish La Liga |
| 27 | Sat 27 Jan | 221-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 28 | Sun 4 Feb | 22 1-1 v GetafeReal Betis 1-1 Getafe | Spanish La Liga |
| 29 | Sun 17 Mar | 22 0-2 v Rayo VallecanoRayo Vallecano 2-0 Real Betis | Spanish La Liga |
| 30 | Sun 31 Mar | 22 2-3 v GironaGirona 3-2 Real Betis | Spanish La Liga |
| 31 | Fri 12 Apr | 222-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
| 32 | Sat 20 Apr | 222-1 v ValenciaValencia 1-2 Real Betis | Spanish La Liga |
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