| 1 | Sat 12 Aug | 41-1 v AFC BournemouthAFC Bournemouth 1-1 West Ham United | Premier League |
| 2 | Sun 20 Aug | 43-1 v ChelseaWest Ham United 3-1 Chelsea | Premier League |
| 3 | Sat 26 Aug | 43-1 v Brighton & Hove AlbionBrighton & Hove Albion 1-3 West Ham United | Premier League |
| 4 | Fri 1 Sep | 42-1 v Luton TownLuton Town 1-2 West Ham United | Premier League |
| 5 | Sat 16 Sep | 41-3 v Manchester CityWest Ham United 1-3 Manchester City | Premier League |
| 6 | Sun 24 Sep | 4 1-3 v LiverpoolLiverpool 3-1 West Ham United | Premier League |
| 7 | Sat 30 Sep | 42-0 v Sheffield UnitedWest Ham United 2-0 Sheffield United | Premier League |
| 8 | Sun 8 Oct | 42-2 v Newcastle UnitedWest Ham United 2-2 Newcastle United | Premier League |
| 9 | Sun 22 Oct | 41-4 v Aston VillaAston Villa 4-1 West Ham United | Premier League |
| 10 | Sun 29 Oct | 40-1 v EvertonWest Ham United 0-1 Everton | Premier League |
| 11 | Sun 12 Nov | 43-2 v Nottingham ForestWest Ham United 3-2 Nottingham Forest | Premier League |
| 12 | Sat 25 Nov | 4 2-1 v BurnleyBurnley 1-2 West Ham United | Premier League |
| 13 | Thu 7 Dec | 42-1 v Tottenham HotspurTottenham Hotspur 1-2 West Ham United | Premier League |
| 14 | Sun 10 Dec | 40-5 v FulhamFulham 5-0 West Ham United | Premier League |
| 15 | Sun 17 Dec | 4 3-0 v Wolverhampton WanderersWest Ham United 3-0 Wolverhampton Wanderers | Premier League |
| 16 | Sat 23 Dec | 42-0 v Manchester UnitedWest Ham United 2-0 Manchester United | Premier League |
| 17 | Sun 7 Jan | 41-1 v Bristol CityWest Ham United 1-1 Bristol City | Emirates FA Cup Third Round |
| 18 | Tue 16 Jan | 40-1 v Bristol CityBristol City 1-0 West Ham United | Emirates FA Cup Third Round Replay |
| 19 | Sun 21 Jan | 42-2 v Sheffield UnitedSheffield United 2-2 West Ham United | Premier League |
| 20 | Thu 1 Feb | 41-1 v AFC BournemouthWest Ham United 1-1 AFC Bournemouth | Premier League |
| 21 | Sun 4 Feb | 40-3 v Manchester UnitedManchester United 3-0 West Ham United | Premier League |
| 22 | Sun 11 Feb | 40-6 v ArsenalWest Ham United 0-6 Arsenal | Premier League |
| 23 | Sat 17 Feb | 4 0-2 v Nottingham ForestNottingham Forest 2-0 West Ham United | Premier League |
| 24 | Mon 26 Feb | 44-2 v BrentfordWest Ham United 4-2 Brentford | Premier League |
| 25 | Sat 2 Mar | 43-1 v EvertonEverton 1-3 West Ham United | Premier League |
| 26 | Thu 7 Mar | 40-1 v SC FreiburgSC Freiburg 1-0 West Ham United | UEFA Europa League Round of 16 |
| 27 | Thu 14 Mar | 45-0 v SC FreiburgWest Ham United 5-0 SC Freiburg | UEFA Europa League Round of 16 |
| 28 | Sun 17 Mar | 41-1 v Aston VillaWest Ham United 1-1 Aston Villa | Premier League |
| 29 | Sat 30 Mar | 43-4 v Newcastle UnitedNewcastle United 4-3 West Ham United | Premier League |
| 30 | Tue 2 Apr | 41-1 v Tottenham HotspurWest Ham United 1-1 Tottenham Hotspur | Premier League |
| 31 | Sat 6 Apr | 42-1 v Wolverhampton WanderersWolverhampton Wanderers 1-2 West Ham United | Premier League |
| 32 | Thu 11 Apr | 40-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-0 West Ham United | UEFA Europa League Quarter Final |
| 33 | Sun 14 Apr | 40-2 v FulhamWest Ham United 0-2 Fulham | Premier League |
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