| 1 | Sat 28 Aug 2021 | 1 1-0 v Celta VigoCelta Vigo 0-1 Athletic Bilbao | Spanish La Liga |
| 2 | Sat 11 Sep 2021 | 12-0 v MallorcaAthletic Bilbao 2-0 Mallorca | Spanish La Liga |
| 3 | Sat 18 Sep 2021 | 10-0 v Atlético MadridAtlético Madrid 0-0 Athletic Bilbao | Spanish La Liga |
| 4 | Tue 21 Sep 2021 | 11-2 v Rayo VallecanoAthletic Bilbao 1-2 Rayo Vallecano | Spanish La Liga |
| 5 | Sat 25 Sep 2021 | 11-1 v ValenciaValencia 1-1 Athletic Bilbao | Spanish La Liga |
| 6 | Fri 1 Oct 2021 | 11-0 v AlavésAthletic Bilbao 1-0 Alavés | Spanish La Liga |
| 7 | Sat 23 Oct 2021 | 12-1 v VillarrealAthletic Bilbao 2-1 Villarreal | Spanish La Liga |
| 8 | Tue 26 Oct 2021 | 11-1 v EspanyolEspanyol 1-1 Athletic Bilbao | Spanish La Liga |
| 9 | Sun 31 Oct 2021 | 11-1 v Real SociedadReal Sociedad 1-1 Athletic Bilbao | Spanish La Liga |
| 10 | Fri 5 Nov 2021 | 10-1 v CádizAthletic Bilbao 0-1 Cádiz | Spanish La Liga |
| 11 | Fri 19 Nov 2021 | 10-0 v LevanteLevante 0-0 Athletic Bilbao | Spanish La Liga |
| 12 | Fri 26 Nov 2021 | 12-2 v GranadaAthletic Bilbao 2-2 Granada | Spanish La Liga |
| 13 | Wed 1 Dec 2021 | 10-1 v Real MadridReal Madrid 1-0 Athletic Bilbao | Spanish La Liga |
| 14 | Mon 6 Dec 2021 | 10-0 v GetafeGetafe 0-0 Athletic Bilbao | Spanish La Liga |
| 15 | Sat 11 Dec 2021 | 10-1 v SevillaAthletic Bilbao 0-1 Sevilla | Spanish La Liga |
| 16 | Mon 3 Jan 2022 | 13-1 v OsasunaOsasuna 1-3 Athletic Bilbao | Spanish La Liga |
| 17 | Sun 9 Jan 2022 | 10-0 v AlavésAlavés 0-0 Athletic Bilbao | Spanish La Liga |
| 18 | Sun 23 Jan 2022 | 1 1-0 v Rayo VallecanoRayo Vallecano 0-1 Athletic Bilbao | Spanish La Liga |
| 19 | Mon 7 Feb 2022 | 12-1 v EspanyolAthletic Bilbao 2-1 Espanyol | Spanish La Liga |
| 20 | Mon 14 Feb 2022 | 12-3 v MallorcaMallorca 3-2 Athletic Bilbao | Spanish La Liga |
| 21 | Sun 20 Feb 2022 | 14-0 v Real SociedadAthletic Bilbao 4-0 Real Sociedad | Spanish La Liga |
| 22 | Sun 27 Feb 2022 | 10-4 v BarcelonaBarcelona 4-0 Athletic Bilbao | Spanish La Liga |
| 23 | Mon 7 Mar 2022 | 13-1 v LevanteAthletic Bilbao 3-1 Levante | Spanish La Liga |
| 24 | Sun 13 Mar 2022 | 10-1 v Real BetisReal Betis 1-0 Athletic Bilbao | Spanish La Liga |
| 25 | Fri 18 Mar 2022 | 11-1 v GetafeAthletic Bilbao 1-1 Getafe | Spanish La Liga |
| 26 | Sun 3 Apr 2022 | 12-1 v ElcheAthletic Bilbao 2-1 Elche | Spanish La Liga |
| 27 | Sat 9 Apr 2022 | 11-1 v VillarrealVillarreal 1-1 Athletic Bilbao | Spanish La Liga |
| 28 | Sun 17 Apr 2022 | 10-2 v Celta VigoAthletic Bilbao 0-2 Celta Vigo | Spanish La Liga |
| 29 | Thu 21 Apr 2022 | 13-2 v CádizCádiz 2-3 Athletic Bilbao | Spanish La Liga |
| 30 | Sat 30 Apr 2022 | 12-0 v Atlético MadridAthletic Bilbao 2-0 Atlético Madrid | Spanish La Liga |
| 31 | Sat 7 May 2022 | 1 0-0 v ValenciaAthletic Bilbao 0-0 Valencia | Spanish La Liga |
| 32 | Tue 10 May 2022 | 10-1 v GranadaGranada 1-0 Athletic Bilbao | Spanish La Liga |
| 33 | Sun 15 May 2022 | 12-0 v OsasunaAthletic Bilbao 2-0 Osasuna | Spanish La Liga |
| 34 | Sun 22 May 2022 | 10-1 v SevillaSevilla 1-0 Athletic Bilbao | Spanish La Liga |
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