| 1 | Tue 26 Oct 2021 | 5 1-1 v EspanyolEspanyol 1-1 Athletic Bilbao | Spanish La Liga |
| 2 | Sun 31 Oct 2021 | 51-1 v Real SociedadReal Sociedad 1-1 Athletic Bilbao | Spanish La Liga |
| 3 | Fri 5 Nov 2021 | 5 0-1 v CádizAthletic Bilbao 0-1 Cádiz | Spanish La Liga |
| 4 | Fri 19 Nov 2021 | 5 0-0 v LevanteLevante 0-0 Athletic Bilbao | Spanish La Liga |
| 5 | Fri 26 Nov 2021 | 52-2 v GranadaAthletic Bilbao 2-2 Granada | Spanish La Liga |
| 6 | Wed 1 Dec 2021 | 50-1 v Real MadridReal Madrid 1-0 Athletic Bilbao | Spanish La Liga |
| 7 | Mon 6 Dec 2021 | 50-0 v GetafeGetafe 0-0 Athletic Bilbao | Spanish La Liga |
| 8 | Sat 11 Dec 2021 | 50-1 v SevillaAthletic Bilbao 0-1 Sevilla | Spanish La Liga |
| 9 | Sun 19 Dec 2021 | 53-2 v Real BetisAthletic Bilbao 3-2 Real Betis | Spanish La Liga |
| 10 | Wed 22 Dec 2021 | 51-2 v Real MadridAthletic Bilbao 1-2 Real Madrid | Spanish La Liga |
| 11 | Mon 3 Jan 2022 | 5 3-1 v OsasunaOsasuna 1-3 Athletic Bilbao | Spanish La Liga |
| 12 | Sun 9 Jan 2022 | 50-0 v AlavésAlavés 0-0 Athletic Bilbao | Spanish La Liga |
| 13 | Sun 27 Feb 2022 | 50-4 v BarcelonaBarcelona 4-0 Athletic Bilbao | Spanish La Liga |
| 14 | Mon 7 Mar 2022 | 53-1 v LevanteAthletic Bilbao 3-1 Levante | Spanish La Liga |
| 15 | Sun 13 Mar 2022 | 50-1 v Real BetisReal Betis 1-0 Athletic Bilbao | Spanish La Liga |
| 16 | Fri 18 Mar 2022 | 5 1-1 v GetafeAthletic Bilbao 1-1 Getafe | Spanish La Liga |
| 17 | Sat 9 Apr 2022 | 51-1 v VillarrealVillarreal 1-1 Athletic Bilbao | Spanish La Liga |
| 18 | Sun 17 Apr 2022 | 50-2 v Celta VigoAthletic Bilbao 0-2 Celta Vigo | Spanish La Liga |
| 19 | Thu 21 Apr 2022 | 53-2 v CádizCádiz 2-3 Athletic Bilbao | Spanish La Liga |
| 20 | Sat 30 Apr 2022 | 52-0 v Atlético MadridAthletic Bilbao 2-0 Atlético Madrid | Spanish La Liga |
| 21 | Sat 7 May 2022 | 5 0-0 v ValenciaAthletic Bilbao 0-0 Valencia | Spanish La Liga |
| 22 | Sun 15 May 2022 | 52-0 v OsasunaAthletic Bilbao 2-0 Osasuna | Spanish La Liga |
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