| 1 | Sun 27 Sep 2020 | 8 6-1 v GranadaAtlético Madrid 6-1 Granada | Spanish La Liga |
| 2 | Wed 30 Sep 2020 | 80-0 v HuescaHuesca 0-0 Atlético Madrid | Spanish La Liga |
| 3 | Sat 3 Oct 2020 | 80-0 v VillarrealAtlético Madrid 0-0 Villarreal | Spanish La Liga |
| 4 | Tue 3 Nov 2020 | 8 1-1 v Lokomotiv MoscowLokomotiv Moscow 1-1 Atlético Madrid | UEFA Champions League Group A |
| 5 | Sat 7 Nov 2020 | 84-0 v CádizAtlético Madrid 4-0 Cádiz | Spanish La Liga |
| 6 | Sat 21 Nov 2020 | 81-0 v BarcelonaAtlético Madrid 1-0 Barcelona | Spanish La Liga |
| 7 | Wed 25 Nov 2020 | 80-0 v Lokomotiv MoscowAtlético Madrid 0-0 Lokomotiv Moscow | UEFA Champions League Group A |
| 8 | Sat 28 Nov 2020 | 8 1-0 v ValenciaValencia 0-1 Atlético Madrid | Spanish La Liga |
| 9 | Tue 1 Dec 2020 | 81-1 v Bayern MunichAtlético Madrid 1-1 Bayern Munich | UEFA Champions League Group A |
| 10 | Sat 5 Dec 2020 | 82-0 v Real ValladolidAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 11 | Wed 9 Dec 2020 | 82-0 v SV Red Bull SalzburgSV Red Bull Salzburg 0-2 Atlético Madrid | UEFA Champions League Group A |
| 12 | Sat 12 Dec 2020 | 80-2 v Real MadridReal Madrid 2-0 Atlético Madrid | Spanish La Liga |
| 13 | Sat 19 Dec 2020 | 83-1 v ElcheAtlético Madrid 3-1 Elche | Spanish La Liga |
| 14 | Tue 22 Dec 2020 | 8 2-0 v Real SociedadReal Sociedad 0-2 Atlético Madrid | Spanish La Liga |
| 15 | Wed 30 Dec 2020 | 81-0 v GetafeAtlético Madrid 1-0 Getafe | Spanish La Liga |
| 16 | Sun 3 Jan 2021 | 82-1 v AlavésAlavés 1-2 Atlético Madrid | Spanish La Liga |
| 17 | Tue 12 Jan 2021 | 82-0 v SevillaAtlético Madrid 2-0 Sevilla | Spanish La Liga |
| 18 | Thu 21 Jan 2021 | 82-1 v EibarEibar 1-2 Atlético Madrid | Spanish La Liga |
| 19 | Sun 31 Jan 2021 | 84-2 v CádizCádiz 2-4 Atlético Madrid | Spanish La Liga |
| 20 | Mon 8 Feb 2021 | 82-2 v Celta VigoAtlético Madrid 2-2 Celta Vigo | Spanish La Liga |
| 21 | Sat 13 Feb 2021 | 8 2-1 v GranadaGranada 1-2 Atlético Madrid | Spanish La Liga |
| 22 | Wed 17 Feb 2021 | 8 1-1 v LevanteLevante 1-1 Atlético Madrid | Spanish La Liga |
| 23 | Tue 23 Feb 2021 | 80-1 v ChelseaAtlético Madrid 0-1 Chelsea | UEFA Champions League Round of 16 |
| 24 | Sun 28 Feb 2021 | 8 2-0 v VillarrealVillarreal 0-2 Atlético Madrid | Spanish La Liga |
| 25 | Sun 7 Mar 2021 | 81-1 v Real MadridAtlético Madrid 1-1 Real Madrid | Spanish La Liga |
| 26 | Wed 10 Mar 2021 | 82-1 v Athletic BilbaoAtlético Madrid 2-1 Athletic Bilbao | Spanish La Liga |
| 27 | Sat 13 Mar 2021 | 80-0 v GetafeGetafe 0-0 Atlético Madrid | Spanish La Liga |
| 28 | Wed 17 Mar 2021 | 8 0-2 v ChelseaChelsea 2-0 Atlético Madrid | UEFA Champions League Round of 16 |
| 29 | Sun 21 Mar 2021 | 8 1-0 v AlavésAtlético Madrid 1-0 Alavés | Spanish La Liga |
| 30 | Sun 4 Apr 2021 | 80-1 v SevillaSevilla 1-0 Atlético Madrid | Spanish La Liga |
| 31 | Sun 11 Apr 2021 | 81-1 v Real BetisReal Betis 1-1 Atlético Madrid | Spanish La Liga |
| 32 | Sun 18 Apr 2021 | 85-0 v EibarAtlético Madrid 5-0 Eibar | Spanish La Liga |
| 33 | Thu 22 Apr 2021 | 8 2-0 v HuescaAtlético Madrid 2-0 Huesca | Spanish La Liga |
| 34 | Sun 25 Apr 2021 | 81-2 v Athletic BilbaoAthletic Bilbao 2-1 Atlético Madrid | Spanish La Liga |
| 35 | Sat 1 May 2021 | 81-0 v ElcheElche 0-1 Atlético Madrid | Spanish La Liga |
| 36 | Sat 8 May 2021 | 8 0-0 v BarcelonaBarcelona 0-0 Atlético Madrid | Spanish La Liga |
| 37 | Wed 12 May 2021 | 82-1 v Real SociedadAtlético Madrid 2-1 Real Sociedad | Spanish La Liga |
| 38 | Sun 16 May 2021 | 82-1 v OsasunaAtlético Madrid 2-1 Osasuna | Spanish La Liga |
| 39 | Sat 22 May 2021 | 82-1 v Real ValladolidReal Valladolid 1-2 Atlético Madrid | Spanish La Liga |
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