| 1 | Sat 30 Oct 2021 | 61-2 v Bristol CityBristol City 2-1 Barnsley | Sky Bet Championship |
| 2 | Wed 3 Nov 2021 | 6 2-1 v Derby CountyBarnsley 2-1 Derby County | Sky Bet Championship |
| 3 | Sat 20 Nov 2021 | 61-4 v FulhamFulham 4-1 Barnsley | Sky Bet Championship |
| 4 | Sat 27 Nov 2021 | 6 0-0 v Peterborough UnitedPeterborough United 0-0 Barnsley | Sky Bet Championship |
| 5 | Sat 4 Dec 2021 | 61-1 v Huddersfield TownBarnsley 1-1 Huddersfield Town | Sky Bet Championship |
| 6 | Sat 11 Dec 2021 | 6 1-2 v Preston North EndPreston North End 2-1 Barnsley | Sky Bet Championship |
| 7 | Fri 17 Dec 2021 | 60-0 v West Bromwich AlbionBarnsley 0-0 West Bromwich Albion | Sky Bet Championship |
| 8 | Wed 29 Dec 2021 | 61-2 v Blackburn RoversBlackburn Rovers 2-1 Barnsley | Sky Bet Championship |
| 9 | Sat 8 Jan 2022 | 65-4 v BarrowBarnsley 5-4 Barrow | Emirates FA Cup Third Round |
| 10 | Sat 22 Jan 2022 | 61-2 v Birmingham CityBirmingham City 2-1 Barnsley | Sky Bet Championship |
| 11 | Tue 25 Jan 2022 | 6 0-3 v Nottingham ForestNottingham Forest 3-0 Barnsley | Sky Bet Championship |
| 12 | Sat 29 Jan 2022 | 60-1 v AFC BournemouthBarnsley 0-1 AFC Bournemouth | Sky Bet Championship |
| 13 | Wed 2 Feb 2022 | 6 0-1 v Cardiff CityBarnsley 0-1 Cardiff City | Sky Bet Championship |
| 14 | Sat 5 Feb 2022 | 60-1 v Huddersfield TownHuddersfield Town 1-0 Barnsley | Emirates FA Cup Fourth Round |
| 15 | Tue 8 Feb 2022 | 61-2 v Luton TownLuton Town 2-1 Barnsley | Sky Bet Championship |
| 16 | Sat 12 Feb 2022 | 61-0 v Queens Park RangersBarnsley 1-0 Queens Park Rangers | Sky Bet Championship |
| 17 | Sat 19 Feb 2022 | 60-1 v Coventry CityCoventry City 1-0 Barnsley | Sky Bet Championship |
| 18 | Tue 22 Feb 2022 | 62-0 v Hull CityHull City 0-2 Barnsley | Sky Bet Championship |
| 19 | Sat 26 Feb 2022 | 63-2 v MiddlesbroughBarnsley 3-2 Middlesbrough | Sky Bet Championship |
| 20 | Sat 5 Mar 2022 | 60-2 v Derby CountyDerby County 2-0 Barnsley | Sky Bet Championship |
| 21 | Tue 8 Mar 2022 | 61-1 v Stoke CityBarnsley 1-1 Stoke City | Sky Bet Championship |
| 22 | Sat 12 Mar 2022 | 61-1 v FulhamBarnsley 1-1 Fulham | Sky Bet Championship |
| 23 | Tue 15 Mar 2022 | 62-0 v Bristol CityBarnsley 2-0 Bristol City | Sky Bet Championship |
| 24 | Sat 19 Mar 2022 | 60-2 v Sheffield UnitedSheffield United 2-0 Barnsley | Sky Bet Championship |
| 25 | Sat 2 Apr 2022 | 6 1-1 v ReadingBarnsley 1-1 Reading | Sky Bet Championship |
| 26 | Sat 9 Apr 2022 | 61-4 v MillwallMillwall 4-1 Barnsley | Sky Bet Championship |
| 27 | Fri 15 Apr 2022 | 61-1 v Swansea CitySwansea City 1-1 Barnsley | Sky Bet Championship |
| 28 | Mon 18 Apr 2022 | 60-2 v Peterborough UnitedBarnsley 0-2 Peterborough United | Sky Bet Championship |
| 29 | Fri 22 Apr 2022 | 61-2 v Huddersfield TownHuddersfield Town 2-1 Barnsley | Sky Bet Championship |
| 30 | Tue 26 Apr 2022 | 6 0-2 v BlackpoolBarnsley 0-2 Blackpool | Sky Bet Championship |
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