| 1 | Sat 26 Sep 2020 | 80-2 v FC AugsburgFC Augsburg 2-0 Borussia Dortmund | German Bundesliga |
| 2 | Sat 17 Oct 2020 | 81-0 v 1899 Hoffenheim1899 Hoffenheim 0-1 Borussia Dortmund | German Bundesliga |
| 3 | Sat 24 Oct 2020 | 83-0 v FC Schalke 04Borussia Dortmund 3-0 FC Schalke 04 | German Bundesliga |
| 4 | Wed 28 Oct 2020 | 82-0 v Zenit St PetersburgBorussia Dortmund 2-0 Zenit St Petersburg | UEFA Champions League Group F |
| 5 | Wed 4 Nov 2020 | 83-0 v Club BruggeClub Brugge 0-3 Borussia Dortmund | UEFA Champions League Group F |
| 6 | Sat 21 Nov 2020 | 85-2 v Hertha BerlinHertha Berlin 2-5 Borussia Dortmund | German Bundesliga |
| 7 | Sat 5 Dec 2020 | 81-1 v Eintracht FrankfurtEintracht Frankfurt 1-1 Borussia Dortmund | German Bundesliga |
| 8 | Sat 30 Jan 2021 | 83-1 v FC AugsburgBorussia Dortmund 3-1 FC Augsburg | German Bundesliga |
| 9 | Sat 6 Feb 2021 | 81-2 v SC FreiburgSC Freiburg 2-1 Borussia Dortmund | German Bundesliga |
| 10 | Sat 13 Feb 2021 | 8 2-2 v 1899 HoffenheimBorussia Dortmund 2-2 1899 Hoffenheim | German Bundesliga |
| 11 | Wed 17 Feb 2021 | 83-2 v SevillaSevilla 2-3 Borussia Dortmund | UEFA Champions League Round of 16 |
| 12 | Sat 20 Feb 2021 | 8 4-0 v FC Schalke 04FC Schalke 04 0-4 Borussia Dortmund | German Bundesliga |
| 13 | Sat 27 Feb 2021 | 83-0 v Arminia BielefeldBorussia Dortmund 3-0 Arminia Bielefeld | German Bundesliga |
| 14 | Sat 6 Mar 2021 | 82-4 v Bayern MunichBayern Munich 4-2 Borussia Dortmund | German Bundesliga |
| 15 | Tue 9 Mar 2021 | 82-2 v SevillaBorussia Dortmund 2-2 Sevilla | UEFA Champions League Round of 16 |
| 16 | Sat 13 Mar 2021 | 82-0 v Hertha BerlinBorussia Dortmund 2-0 Hertha Berlin | German Bundesliga |
| 17 | Sat 20 Mar 2021 | 82-2 v 1. FC Köln1. FC Köln 2-2 Borussia Dortmund | German Bundesliga |
| 18 | Sat 3 Apr 2021 | 81-2 v Eintracht FrankfurtBorussia Dortmund 1-2 Eintracht Frankfurt | German Bundesliga |
| 19 | Tue 6 Apr 2021 | 81-2 v Manchester CityManchester City 2-1 Borussia Dortmund | UEFA Champions League Quarter Final |
| 20 | Sat 10 Apr 2021 | 83-2 v VfB StuttgartVfB Stuttgart 2-3 Borussia Dortmund | German Bundesliga |
| 21 | Wed 14 Apr 2021 | 81-2 v Manchester CityBorussia Dortmund 1-2 Manchester City | UEFA Champions League Quarter Final |
| 22 | Sun 18 Apr 2021 | 8 4-1 v Werder BremenBorussia Dortmund 4-1 Werder Bremen | German Bundesliga |
| 23 | Wed 21 Apr 2021 | 82-0 v 1. FC Union BerlinBorussia Dortmund 2-0 1. FC Union Berlin | German Bundesliga |
| 24 | Sat 24 Apr 2021 | 82-0 v VfL WolfsburgVfL Wolfsburg 0-2 Borussia Dortmund | German Bundesliga |
| 25 | Sat 8 May 2021 | 83-2 v RB LeipzigBorussia Dortmund 3-2 RB Leipzig | German Bundesliga |
| 26 | Sun 16 May 2021 | 83-1 v Mainz 05Mainz 05 1-3 Borussia Dortmund | German Bundesliga |
| 27 | Sat 22 May 2021 | 83-1 v Bayer 04 LeverkusenBorussia Dortmund 3-1 Bayer 04 Leverkusen | German Bundesliga |
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