| 1 | 14/8/2021 | 43-0 v Crystal PalaceChelsea 3-0 Crystal Palace | Premier League |
| 2 | 22/8/2021 | 42-0 v ArsenalArsenal 0-2 Chelsea | Premier League |
| 3 | 28/8/2021 | 41-1 v LiverpoolLiverpool 1-1 Chelsea | Premier League |
| 4 | 11/9/2021 | 43-0 v Aston VillaChelsea 3-0 Aston Villa | Premier League |
| 5 | 14/9/2021 | 41-0 v Zenit St PetersburgChelsea 1-0 Zenit St Petersburg | UEFA Champions League Group H |
| 6 | 19/9/2021 | 43-0 v Tottenham HotspurTottenham Hotspur 0-3 Chelsea | Premier League |
| 7 | 25/9/2021 | 4 0-1 v Manchester CityChelsea 0-1 Manchester City | Premier League |
| 8 | 29/9/2021 | 40-1 v JuventusJuventus 1-0 Chelsea | UEFA Champions League Group H |
| 9 | 2/10/2021 | 43-1 v SouthamptonChelsea 3-1 Southampton | Premier League |
| 10 | 16/10/2021 | 41-0 v BrentfordBrentford 0-1 Chelsea | Premier League |
| 11 | 20/10/2021 | 44-0 v Malmö FFChelsea 4-0 Malmö FF | UEFA Champions League Group H |
| 12 | 23/10/2021 | 47-0 v Norwich CityChelsea 7-0 Norwich City | Premier League |
| 13 | 30/10/2021 | 43-0 v Newcastle UnitedNewcastle United 0-3 Chelsea | Premier League |
| 14 | 2/11/2021 | 41-0 v Malmö FFMalmö FF 0-1 Chelsea | UEFA Champions League Group H |
| 15 | 6/11/2021 | 41-1 v BurnleyChelsea 1-1 Burnley | Premier League |
| 16 | 20/11/2021 | 43-0 v Leicester CityLeicester City 0-3 Chelsea | Premier League |
| 17 | 23/11/2021 | 44-0 v JuventusChelsea 4-0 Juventus | UEFA Champions League Group H |
| 18 | 28/11/2021 | 41-1 v Manchester UnitedChelsea 1-1 Manchester United | Premier League |
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