| 1 | Sat 12 Feb 2022 | 30-0 v MargateEast Thurrock United 0-0 Margate | Isthmian League - Premier Division |
| 2 | Sat 19 Feb 2022 | 30-6 v HornchurchHornchurch 6-0 East Thurrock United | Isthmian League - Premier Division |
| 3 | Tue 22 Feb 2022 | 41-1 v BarkingBarking 1-1 East Thurrock United | Velocity Trophy Fourth Round |
| 4 | Sat 26 Feb 2022 | 31-0 v Carshalton AthleticEast Thurrock United 1-0 Carshalton Athletic | Isthmian League - Premier Division |
| 5 | Tue 1 Mar 2022 | 3 1-3 v Folkestone InvictaFolkestone Invicta 3-1 East Thurrock United | Isthmian League - Premier Division |
| 6 | Tue 8 Mar 2022 | 30-1 v WorthingEast Thurrock United 0-1 Worthing | Isthmian League - Premier Division |
| 7 | Sat 12 Mar 2022 | 32-1 v KingstonianEast Thurrock United 2-1 Kingstonian | Isthmian League - Premier Division |
| 8 | Sat 19 Mar 2022 | 31-3 v LeatherheadLeatherhead 3-1 East Thurrock United | Isthmian League - Premier Division |
| 9 | Tue 22 Mar 2022 | 30-2 v CheshuntEast Thurrock United 0-2 Cheshunt | Isthmian League - Premier Division |
| 10 | Sat 26 Mar 2022 | 32-1 v Corinthian-CasualsCorinthian-Casuals 1-2 East Thurrock United | Isthmian League - Premier Division |
| 11 | Tue 29 Mar 2022 | 31-0 v Potters Bar TownEast Thurrock United 1-0 Potters Bar Town | Isthmian League - Premier Division |
| 12 | Sat 2 Apr 2022 | 32-0 v MersthamEast Thurrock United 2-0 Merstham | Isthmian League - Premier Division |
| 13 | Sat 9 Apr 2022 | 31-1 v Bognor Regis TownBognor Regis Town 1-1 East Thurrock United | Isthmian League - Premier Division |
| 14 | Sat 16 Apr 2022 | 32-2 v Wingate & FinchleyEast Thurrock United 2-2 Wingate & Finchley | Isthmian League - Premier Division |
| 15 | Wed 20 Apr 2022 | 31-4 v Cray WanderersCray Wanderers 4-1 East Thurrock United | Isthmian League - Premier Division |
| 16 | Sat 23 Apr 2022 | 32-3 v HorshamEast Thurrock United 2-3 Horsham | Isthmian League - Premier Division |
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