| 1 | Sat 14 Aug 2021 | 43-1 v SouthamptonEverton 3-1 Southampton | Premier League |
| 2 | Tue 24 Aug 2021 | 42-1 v Huddersfield TownHuddersfield Town 1-2 Everton | Carabao Cup Second Round |
| 3 | Sat 28 Aug 2021 | 42-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-2 Everton | Premier League |
| 4 | Tue 21 Sep 2021 | 42-2 v Queens Park RangersQueens Park Rangers 2-2 Everton | Carabao Cup Third Round |
| 5 | Mon 1 Nov 2021 | 41-2 v Wolverhampton WanderersWolverhampton Wanderers 2-1 Everton | Premier League |
| 6 | Sun 7 Nov 2021 | 4 0-0 v Tottenham HotspurEverton 0-0 Tottenham Hotspur | Premier League |
| 7 | Mon 6 Dec 2021 | 42-1 v ArsenalEverton 2-1 Arsenal | Premier League |
| 8 | Sun 12 Dec 2021 | 41-3 v Crystal PalaceCrystal Palace 3-1 Everton | Premier League |
| 9 | Thu 16 Dec 2021 | 4 1-1 v ChelseaChelsea 1-1 Everton | Premier League |
| 10 | Sun 2 Jan 2022 | 42-3 v Brighton & Hove AlbionEverton 2-3 Brighton & Hove Albion | Premier League |
| 11 | Sat 22 Jan 2022 | 40-1 v Aston VillaEverton 0-1 Aston Villa | Premier League |
| 12 | Sat 5 Feb 2022 | 44-1 v BrentfordEverton 4-1 Brentford | Emirates FA Cup Fourth Round |
| 13 | Tue 8 Feb 2022 | 4 1-3 v Newcastle UnitedNewcastle United 3-1 Everton | Premier League |
| 14 | Sat 12 Feb 2022 | 43-0 v Leeds UnitedEverton 3-0 Leeds United | Premier League |
| 15 | Sat 19 Feb 2022 | 40-2 v SouthamptonSouthampton 2-0 Everton | Premier League |
| 16 | Sat 26 Feb 2022 | 40-1 v Manchester CityEverton 0-1 Manchester City | Premier League |
| 17 | Mon 7 Mar 2022 | 40-5 v Tottenham HotspurTottenham Hotspur 5-0 Everton | Premier League |
| 18 | Sun 13 Mar 2022 | 4 0-1 v Wolverhampton WanderersEverton 0-1 Wolverhampton Wanderers | Premier League |
| 19 | Thu 17 Mar 2022 | 41-0 v Newcastle UnitedEverton 1-0 Newcastle United | Premier League |
| 20 | Sun 20 Mar 2022 | 40-4 v Crystal PalaceCrystal Palace 4-0 Everton | Emirates FA Cup Sixth Round |
| 21 | Wed 6 Apr 2022 | 4 2-3 v BurnleyBurnley 3-2 Everton | Premier League |
| 22 | Sun 24 Apr 2022 | 40-2 v LiverpoolLiverpool 2-0 Everton | Premier League |
| 23 | Sun 1 May 2022 | 4 1-0 v ChelseaEverton 1-0 Chelsea | Premier League |
| 24 | Sun 8 May 2022 | 42-1 v Leicester CityLeicester City 1-2 Everton | Premier League |
| 25 | Wed 11 May 2022 | 4 0-0 v WatfordWatford 0-0 Everton | Premier League |
| 26 | Sun 15 May 2022 | 42-3 v BrentfordEverton 2-3 Brentford | Premier League |
| 27 | Thu 19 May 2022 | 43-2 v Crystal PalaceEverton 3-2 Crystal Palace | Premier League |
| 28 | Sun 22 May 2022 | 41-5 v ArsenalArsenal 5-1 Everton | Premier League |
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