| 1 | Sun 24 Jan 2021 | 250-1 v VVV VenloFC Twente 0-1 VVV Venlo | Dutch Eredivisie |
| 2 | Thu 28 Jan 2021 | 250-0 v Sparta RotterdamSparta Rotterdam 0-0 FC Twente | Dutch Eredivisie |
| 3 | Sun 31 Jan 2021 | 250-0 v sc HeerenveenFC Twente 0-0 sc Heerenveen | Dutch Eredivisie |
| 4 | Sat 6 Feb 2021 | 250-3 v PSV EindhovenPSV Eindhoven 3-0 FC Twente | Dutch Eredivisie |
| 5 | Sun 14 Feb 2021 | 252-0 v VitesseVitesse 0-2 FC Twente | Dutch Eredivisie |
| 6 | Sun 21 Feb 2021 | 252-2 v FeyenoordFC Twente 2-2 Feyenoord | Dutch Eredivisie |
| 7 | Sat 27 Feb 2021 | 252-2 v Heracles AlmeloHeracles Almelo 2-2 FC Twente | Dutch Eredivisie |
| 8 | Sat 6 Mar 2021 | 251-1 v Willem IIFC Twente 1-1 Willem II | Dutch Eredivisie |
| 9 | Sat 13 Mar 2021 | 251-4 v AZ AlkmaarAZ Alkmaar 4-1 FC Twente | Dutch Eredivisie |
| 10 | Fri 19 Mar 2021 | 250-0 v sc Heerenveensc Heerenveen 0-0 FC Twente | Dutch Eredivisie |
| 11 | Sat 3 Apr 2021 | 251-2 v VitesseFC Twente 1-2 Vitesse | Dutch Eredivisie |
| 12 | Sat 10 Apr 2021 | 250-1 v PEC ZwollePEC Zwolle 1-0 FC Twente | Dutch Eredivisie |
| 13 | Sun 25 Apr 2021 | 251-2 v FC UtrechtFC Twente 1-2 FC Utrecht | Dutch Eredivisie |
| 14 | Sat 1 May 2021 | 250-3 v Fortuna SittardFortuna Sittard 3-0 FC Twente | Dutch Eredivisie |
| 15 | Sat 8 May 2021 | 251-1 v Heracles AlmeloFC Twente 1-1 Heracles Almelo | Dutch Eredivisie |
| 16 | Thu 13 May 2021 | 251-2 v RKC WaalwijkRKC Waalwijk 2-1 FC Twente | Dutch Eredivisie |
| 17 | Sun 16 May 2021 | 253-2 v ADO Den HaagFC Twente 3-2 ADO Den Haag | Dutch Eredivisie |
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