| 1 | Fri 13 Aug 2021 | 290-1 v sc HeerenveenGo Ahead Eagles 0-1 sc Heerenveen | Dutch Eredivisie |
| 2 | Sun 22 Aug 2021 | 290-2 v FeyenoordFeyenoord 2-0 Go Ahead Eagles | Dutch Eredivisie |
| 3 | Sat 28 Aug 2021 | 292-0 v Sparta RotterdamGo Ahead Eagles 2-0 Sparta Rotterdam | Dutch Eredivisie |
| 4 | Sun 19 Sep 2021 | 291-0 v PEC ZwolleGo Ahead Eagles 1-0 PEC Zwolle | Dutch Eredivisie |
| 5 | Wed 22 Sep 2021 | 291-2 v PSV EindhovenGo Ahead Eagles 1-2 PSV Eindhoven | Dutch Eredivisie |
| 6 | Sun 26 Sep 2021 | 290-5 v AZ AlkmaarAZ Alkmaar 5-0 Go Ahead Eagles | Dutch Eredivisie |
| 7 | Sat 2 Oct 2021 | 291-1 v RKC WaalwijkRKC Waalwijk 1-1 Go Ahead Eagles | Dutch Eredivisie |
| 8 | Sat 16 Oct 2021 | 294-2 v Heracles AlmeloGo Ahead Eagles 4-2 Heracles Almelo | Dutch Eredivisie |
| 9 | Sun 24 Oct 2021 | 292-1 v VitesseVitesse 1-2 Go Ahead Eagles | Dutch Eredivisie |
| 10 | Sun 31 Oct 2021 | 294-3 v Fortuna SittardGo Ahead Eagles 4-3 Fortuna Sittard | Dutch Eredivisie |
| 11 | Sun 7 Nov 2021 | 290-0 v AjaxAjax 0-0 Go Ahead Eagles | Dutch Eredivisie |
| 12 | Sun 6 Feb 2022 | 291-2 v FC GroningenFC Groningen 2-1 Go Ahead Eagles | Dutch Eredivisie |
| 13 | Sun 13 Feb 2022 | 291-4 v AZ AlkmaarGo Ahead Eagles 1-4 AZ Alkmaar | Dutch Eredivisie |
| 14 | Sat 5 Mar 2022 | 291-1 v FC UtrechtGo Ahead Eagles 1-1 FC Utrecht | Dutch Eredivisie |
| 15 | Sat 12 Mar 2022 | 290-1 v Sparta RotterdamSparta Rotterdam 1-0 Go Ahead Eagles | Dutch Eredivisie |
| 16 | Sun 3 Apr 2022 | 291-0 v PEC ZwollePEC Zwolle 0-1 Go Ahead Eagles | Dutch Eredivisie |
| 17 | Fri 8 Apr 2022 | 294-0 v Willem IIGo Ahead Eagles 4-0 Willem II | Dutch Eredivisie |
| 18 | Sun 24 Apr 2022 | 290-1 v Fortuna SittardFortuna Sittard 1-0 Go Ahead Eagles | Dutch Eredivisie |
| 19 | Sun 8 May 2022 | 290-1 v NEC NijmegenNEC Nijmegen 1-0 Go Ahead Eagles | Dutch Eredivisie |
| 20 | Wed 11 May 2022 | 290-1 v FeyenoordGo Ahead Eagles 0-1 Feyenoord | Dutch Eredivisie |
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