| 1 | Tue 27 Jul 2021 | 31-2 v WareWare 2-1 Grays Athletic | Friendly |
| 2 | Sat 31 Jul 2021 | 111-1 v Braintree TownGrays Athletic 1-1 Braintree Town | Friendly |
| 3 | Wed 4 Aug 2021 | 111-4 v HornchurchGrays Athletic 1-4 Hornchurch | Friendly |
| 4 | Sun 22 Aug 2021 | 171-2 v Baldock TownBaldock Town 2-1 Grays Athletic | Emirates FA Cup Preliminary Round |
| 5 | Sat 28 Aug 2021 | 117-0 v Basildon UnitedBasildon United 0-7 Grays Athletic | Isthmian League - North Division |
| 6 | Mon 30 Aug 2021 | 112-1 v AveleyGrays Athletic 2-1 Aveley | Isthmian League - North Division |
| 7 | Fri 10 Sep 2021 | 111-2 v Maldon & TiptreeMaldon & Tiptree 2-1 Grays Athletic | Isthmian League - North Division |
| 8 | Sat 16 Oct 2021 | 191-0 v FisherGrays Athletic 1-0 Fisher | Friendly |
| 9 | Sat 1 Jan 2022 | 161-3 v Canvey IslandGrays Athletic 1-3 Canvey Island | Isthmian League - North Division |
| 10 | Mon 3 Jan 2022 | 120-1 v Brentwood TownBrentwood Town 1-0 Grays Athletic | Isthmian League - North Division |
| 11 | Tue 25 Jan 2022 | 161-5 v BarkingBarking 5-1 Grays Athletic | Essex County Cup Fourth Round |
| 12 | Tue 15 Feb 2022 | 31-0 v BarkingBarking 0-1 Grays Athletic | Isthmian League - North Division |
| 13 | Sat 19 Feb 2022 | 31-0 v Heybridge SwiftsGrays Athletic 1-0 Heybridge Swifts | Isthmian League - North Division |
| 14 | Sat 12 Mar 2022 | 150-1 v Stowmarket TownStowmarket Town 1-0 Grays Athletic | Isthmian League - North Division |
| 15 | Sat 19 Mar 2022 | 32-3 v Witham TownGrays Athletic 2-3 Witham Town | Isthmian League - North Division |
| 16 | Sat 26 Mar 2022 | 71-1 v TilburyTilbury 1-1 Grays Athletic | Isthmian League - North Division |
| 17 | Tue 29 Mar 2022 | 7 1-0 v Hullbridge SportsHullbridge Sports 0-1 Grays Athletic | Isthmian League - North Division |
| 18 | Sat 2 Apr 2022 | 72-1 v Hashtag UnitedGrays Athletic 2-1 Hashtag United | Isthmian League - North Division |
| 19 | Sat 9 Apr 2022 | 11 1-0 v Dereham TownDereham Town 0-1 Grays Athletic | Isthmian League - North Division |
| 20 | Sat 16 Apr 2022 | 110-2 v Brentwood TownGrays Athletic 0-2 Brentwood Town | Isthmian League - North Division |
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