| 1 | Sat 14 Aug 2021 | 11-5 v Manchester UnitedManchester United 5-1 Leeds United | Premier League |
| 2 | Sat 21 Aug 2021 | 12-2 v EvertonLeeds United 2-2 Everton | Premier League |
| 3 | Tue 24 Aug 2021 | 13-0 v Crewe AlexandraLeeds United 3-0 Crewe Alexandra | Carabao Cup Second Round |
| 4 | Sun 29 Aug 2021 | 11-1 v BurnleyBurnley 1-1 Leeds United | Premier League |
| 5 | Sun 12 Sep 2021 | 10-3 v LiverpoolLeeds United 0-3 Liverpool | Premier League |
| 6 | Fri 17 Sep 2021 | 11-1 v Newcastle UnitedNewcastle United 1-1 Leeds United | Premier League |
| 7 | Tue 21 Sep 2021 | 10-0 v FulhamFulham 0-0 Leeds United | Carabao Cup Third Round |
| 8 | Sat 25 Sep 2021 | 1 1-2 v West Ham UnitedLeeds United 1-2 West Ham United | Premier League |
| 9 | Sat 2 Oct 2021 | 11-0 v WatfordLeeds United 1-0 Watford | Premier League |
| 10 | Sat 16 Oct 2021 | 10-1 v SouthamptonSouthampton 1-0 Leeds United | Premier League |
| 11 | Sat 23 Oct 2021 | 11-1 v Wolverhampton WanderersLeeds United 1-1 Wolverhampton Wanderers | Premier League |
| 12 | Tue 26 Oct 2021 | 10-2 v ArsenalArsenal 2-0 Leeds United | Carabao Cup Round of 16 |
| 13 | Sun 31 Oct 2021 | 12-1 v Norwich CityNorwich City 1-2 Leeds United | Premier League |
| 14 | Sun 7 Nov 2021 | 11-1 v Leicester CityLeeds United 1-1 Leicester City | Premier League |
| 15 | Sun 21 Nov 2021 | 11-2 v Tottenham HotspurTottenham Hotspur 2-1 Leeds United | Premier League |
| 16 | Sat 27 Nov 2021 | 10-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-0 Leeds United | Premier League |
| 17 | Tue 30 Nov 2021 | 11-0 v Crystal PalaceLeeds United 1-0 Crystal Palace | Premier League |
| 18 | Sun 5 Dec 2021 | 12-2 v BrentfordLeeds United 2-2 Brentford | Premier League |
| 19 | Sat 11 Dec 2021 | 1 2-3 v ChelseaChelsea 3-2 Leeds United | Premier League |
| 20 | Tue 14 Dec 2021 | 10-7 v Manchester CityManchester City 7-0 Leeds United | Premier League |
| 21 | Sat 18 Dec 2021 | 11-4 v ArsenalLeeds United 1-4 Arsenal | Premier League |
| 22 | Sun 2 Jan 2022 | 13-1 v BurnleyLeeds United 3-1 Burnley | Premier League |
| 23 | Sun 9 Jan 2022 | 10-2 v West Ham UnitedWest Ham United 2-0 Leeds United | Emirates FA Cup Third Round |
| 24 | Sun 16 Jan 2022 | 13-2 v West Ham UnitedWest Ham United 2-3 Leeds United | Premier League |
| 25 | Sat 22 Jan 2022 | 10-1 v Newcastle UnitedLeeds United 0-1 Newcastle United | Premier League |
| 26 | Wed 9 Feb 2022 | 13-3 v Aston VillaAston Villa 3-3 Leeds United | Premier League |
| 27 | Sat 12 Feb 2022 | 10-3 v EvertonEverton 3-0 Leeds United | Premier League |
| 28 | Sun 20 Feb 2022 | 12-4 v Manchester UnitedLeeds United 2-4 Manchester United | Premier League |
| 29 | Wed 23 Feb 2022 | 10-6 v LiverpoolLiverpool 6-0 Leeds United | Premier League |
| 30 | Sat 26 Feb 2022 | 10-4 v Tottenham HotspurLeeds United 0-4 Tottenham Hotspur | Premier League |
| 31 | Sat 5 Mar 2022 | 10-1 v Leicester CityLeicester City 1-0 Leeds United | Premier League |
| 32 | Thu 10 Mar 2022 | 10-3 v Aston VillaLeeds United 0-3 Aston Villa | Premier League |
| 33 | Sun 13 Mar 2022 | 12-1 v Norwich CityLeeds United 2-1 Norwich City | Premier League |
| 34 | Fri 18 Mar 2022 | 13-2 v Wolverhampton WanderersWolverhampton Wanderers 2-3 Leeds United | Premier League |
| 35 | Sat 2 Apr 2022 | 11-1 v SouthamptonLeeds United 1-1 Southampton | Premier League |
| 36 | Sat 9 Apr 2022 | 13-0 v WatfordWatford 0-3 Leeds United | Premier League |
| 37 | Mon 25 Apr 2022 | 10-0 v Crystal PalaceCrystal Palace 0-0 Leeds United | Premier League |
| 38 | Sat 30 Apr 2022 | 10-4 v Manchester CityLeeds United 0-4 Manchester City | Premier League |
| 39 | Sun 8 May 2022 | 11-2 v ArsenalArsenal 2-1 Leeds United | Premier League |
| 40 | Wed 11 May 2022 | 10-3 v ChelseaLeeds United 0-3 Chelsea | Premier League |
| 41 | Sun 15 May 2022 | 11-1 v Brighton & Hove AlbionLeeds United 1-1 Brighton & Hove Albion | Premier League |
| 42 | Sun 22 May 2022 | 12-1 v BrentfordBrentford 1-2 Leeds United | Premier League |
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