| 1 | Sat 14 Aug 2021 | 7 3-0 v Norwich CityNorwich City 0-3 Liverpool | Premier League |
| 2 | Wed 15 Sep 2021 | 7 3-2 v AC MilanLiverpool 3-2 AC Milan | UEFA Champions League Group B |
| 3 | Sat 18 Sep 2021 | 73-0 v Crystal PalaceLiverpool 3-0 Crystal Palace | Premier League |
| 4 | Tue 28 Sep 2021 | 75-1 v FC PortoFC Porto 1-5 Liverpool | UEFA Champions League Group B |
| 5 | Sun 3 Oct 2021 | 7 2-2 v Manchester CityLiverpool 2-2 Manchester City | Premier League |
| 6 | Sat 16 Oct 2021 | 75-0 v WatfordWatford 0-5 Liverpool | Premier League |
| 7 | Tue 19 Oct 2021 | 7 3-2 v Atlético MadridAtlético Madrid 2-3 Liverpool | UEFA Champions League Group B |
| 8 | Sun 24 Oct 2021 | 75-0 v Manchester UnitedManchester United 0-5 Liverpool | Premier League |
| 9 | Wed 24 Nov 2021 | 7 2-0 v FC PortoLiverpool 2-0 FC Porto | UEFA Champions League Group B |
| 10 | Sat 27 Nov 2021 | 74-0 v SouthamptonLiverpool 4-0 Southampton | Premier League |
| 11 | Wed 1 Dec 2021 | 74-1 v EvertonEverton 1-4 Liverpool | Premier League |
| 12 | Sat 4 Dec 2021 | 71-0 v Wolverhampton WanderersWolverhampton Wanderers 0-1 Liverpool | Premier League |
| 13 | Sat 11 Dec 2021 | 71-0 v Aston VillaLiverpool 1-0 Aston Villa | Premier League |
| 14 | Thu 16 Dec 2021 | 73-1 v Newcastle UnitedLiverpool 3-1 Newcastle United | Premier League |
| 15 | Sun 19 Dec 2021 | 72-2 v Tottenham HotspurTottenham Hotspur 2-2 Liverpool | Premier League |
| 16 | Wed 22 Dec 2021 | 73-3 v Leicester CityLiverpool 3-3 Leicester City | Carabao Cup Quarter Final |
| 17 | Tue 28 Dec 2021 | 70-1 v Leicester CityLeicester City 1-0 Liverpool | Premier League |
| 18 | Sun 2 Jan 2022 | 72-2 v ChelseaChelsea 2-2 Liverpool | Premier League |
| 19 | Thu 13 Jan 2022 | 70-0 v ArsenalLiverpool 0-0 Arsenal | Carabao Cup Semi Final |
| 20 | Sun 16 Jan 2022 | 73-0 v BrentfordLiverpool 3-0 Brentford | Premier League |
| 21 | Thu 20 Jan 2022 | 72-0 v ArsenalArsenal 0-2 Liverpool | Carabao Cup Semi Final |
| 22 | Sun 23 Jan 2022 | 73-1 v Crystal PalaceCrystal Palace 1-3 Liverpool | Premier League |
| 23 | Sun 6 Feb 2022 | 73-1 v Cardiff CityLiverpool 3-1 Cardiff City | Emirates FA Cup Fourth Round |
| 24 | Sun 13 Feb 2022 | 71-0 v BurnleyBurnley 0-1 Liverpool | Premier League |
| 25 | Wed 16 Feb 2022 | 72-0 v Inter MilanInter Milan 0-2 Liverpool | UEFA Champions League Round of 16 |
| 26 | Wed 23 Feb 2022 | 76-0 v Leeds UnitedLiverpool 6-0 Leeds United | Premier League |
| 27 | Sun 27 Feb 2022 | 70-0 v ChelseaChelsea 0-0 Liverpool | Carabao Cup Final |
| 28 | Wed 2 Mar 2022 | 72-1 v Norwich CityLiverpool 2-1 Norwich City | Emirates FA Cup Fifth Round |
| 29 | Sat 5 Mar 2022 | 71-0 v West Ham UnitedLiverpool 1-0 West Ham United | Premier League |
| 30 | Sat 12 Mar 2022 | 72-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-2 Liverpool | Premier League |
| 31 | Sat 2 Apr 2022 | 72-0 v WatfordLiverpool 2-0 Watford | Premier League |
| 32 | Tue 5 Apr 2022 | 73-1 v BenficaBenfica 1-3 Liverpool | UEFA Champions League Quarter Final |
| 33 | Wed 13 Apr 2022 | 73-3 v BenficaLiverpool 3-3 Benfica | UEFA Champions League Quarter Final |
| 34 | Tue 19 Apr 2022 | 74-0 v Manchester UnitedLiverpool 4-0 Manchester United | Premier League |
| 35 | Sat 30 Apr 2022 | 71-0 v Newcastle UnitedNewcastle United 0-1 Liverpool | Premier League |
| 36 | Tue 3 May 2022 | 73-2 v VillarrealVillarreal 2-3 Liverpool | UEFA Champions League Semi Final |
| 37 | Sat 14 May 2022 | 70-0 v ChelseaChelsea 0-0 Liverpool | Emirates FA Cup Final |
| 38 | Tue 17 May 2022 | 72-1 v SouthamptonSouthampton 1-2 Liverpool | Premier League |
| 39 | Sun 22 May 2022 | 73-1 v Wolverhampton WanderersLiverpool 3-1 Wolverhampton Wanderers | Premier League |
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