| 1 | 8/8/2021 | 171-1 v Saint ÉtienneSaint Étienne 1-1 Lorient | French Ligue 1 |
| 2 | 13/8/2021 | 17 1-0 v MonacoLorient 1-0 Monaco | French Ligue 1 |
| 3 | 22/8/2021 | 17 1-3 v MontpellierMontpellier 3-1 Lorient | French Ligue 1 |
| 4 | 10/9/2021 | 172-1 v LilleLorient 2-1 Lille | French Ligue 1 |
| 5 | 19/9/2021 | 170-0 v ReimsReims 0-0 Lorient | French Ligue 1 |
| 6 | 22/9/2021 | 171-0 v NiceLorient 1-0 Nice | French Ligue 1 |
| 7 | 25/9/2021 | 171-1 v LyonLyon 1-1 Lorient | French Ligue 1 |
| 8 | 17/10/2021 | 171-4 v MarseilleMarseille 4-1 Lorient | French Ligue 1 |
| 9 | 24/10/2021 | 171-1 v BordeauxLorient 1-1 Bordeaux | French Ligue 1 |
| 10 | 31/10/2021 | 170-4 v StrasbourgStrasbourg 4-0 Lorient | French Ligue 1 |
| 11 | 7/11/2021 | 171-2 v BrestLorient 1-2 Brest | French Ligue 1 |
| 12 | 21/11/2021 | 170-1 v AngersAngers 1-0 Lorient | French Ligue 1 |
| 13 | 28/11/2021 | 170-2 v RennesLorient 0-2 Rennes | French Ligue 1 |
| 14 | 5/12/2021 | 170-1 v NantesLorient 0-1 Nantes | French Ligue 1 |
| 15 | 12/12/2021 | 171-4 v MetzMetz 4-1 Lorient | French Ligue 1 |
| 16 | 22/12/2021 | 171-1 v Paris St GermainLorient 1-1 Paris St Germain | French Ligue 1 |
| 17 | 16/1/2022 | 170-0 v AngersLorient 0-0 Angers | French Ligue 1 |
| 18 | 19/1/2022 | 171-3 v LilleLille 3-1 Lorient | French Ligue 1 |
| 19 | 23/1/2022 | 172-4 v NantesNantes 4-2 Lorient | French Ligue 1 |
| 20 | 6/2/2022 | 172-0 v LensLorient 2-0 Lens | French Ligue 1 |
| 21 | 13/2/2022 | 170-0 v MonacoMonaco 0-0 Lorient | French Ligue 1 |
| 22 | 20/2/2022 | 170-1 v MontpellierLorient 0-1 Montpellier | French Ligue 1 |
| 23 | 27/2/2022 | 17 1-0 v BrestBrest 0-1 Lorient | French Ligue 1 |
| 24 | 4/3/2022 | 171-4 v LyonLorient 1-4 Lyon | French Ligue 1 |
| 25 | 13/3/2022 | 172-0 v ClermontClermont 0-2 Lorient | French Ligue 1 |
| 26 | 20/3/2022 | 170-0 v StrasbourgLorient 0-0 Strasbourg | French Ligue 1 |
| 27 | 3/4/2022 | 171-5 v Paris St GermainParis St Germain 5-1 Lorient | French Ligue 1 |
| 28 | 8/4/2022 | 176-2 v Saint ÉtienneLorient 6-2 Saint Étienne | French Ligue 1 |
| 29 | 17/4/2022 | 171-2 v NiceNice 2-1 Lorient | French Ligue 1 |
| 30 | 20/4/2022 | 17 1-0 v MetzLorient 1-0 Metz | French Ligue 1 |
| 31 | 24/4/2022 | 170-5 v RennesRennes 5-0 Lorient | French Ligue 1 |
| 32 | 1/5/2022 | 171-2 v ReimsLorient 1-2 Reims | French Ligue 1 |
| 33 | 8/5/2022 | 170-3 v MarseilleLorient 0-3 Marseille | French Ligue 1 |
| 34 | 14/5/2022 | 170-0 v BordeauxBordeaux 0-0 Lorient | French Ligue 1 |
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