| 1 | 8/8/2021 | 301-1 v Saint ÉtienneSaint Étienne 1-1 Lorient | French Ligue 1 |
| 2 | 13/8/2021 | 301-0 v MonacoLorient 1-0 Monaco | French Ligue 1 |
| 3 | 22/8/2021 | 301-3 v MontpellierMontpellier 3-1 Lorient | French Ligue 1 |
| 4 | 29/8/2021 | 30 2-2 v LensLens 2-2 Lorient | French Ligue 1 |
| 5 | 10/9/2021 | 302-1 v LilleLorient 2-1 Lille | French Ligue 1 |
| 6 | 19/9/2021 | 300-0 v ReimsReims 0-0 Lorient | French Ligue 1 |
| 7 | 22/9/2021 | 301-0 v NiceLorient 1-0 Nice | French Ligue 1 |
| 8 | 25/9/2021 | 301-1 v LyonLyon 1-1 Lorient | French Ligue 1 |
| 9 | 17/10/2021 | 301-4 v MarseilleMarseille 4-1 Lorient | French Ligue 1 |
| 10 | 24/10/2021 | 301-1 v BordeauxLorient 1-1 Bordeaux | French Ligue 1 |
| 11 | 31/10/2021 | 300-4 v StrasbourgStrasbourg 4-0 Lorient | French Ligue 1 |
| 12 | 7/11/2021 | 301-2 v BrestLorient 1-2 Brest | French Ligue 1 |
| 13 | 21/11/2021 | 300-1 v AngersAngers 1-0 Lorient | French Ligue 1 |
| 14 | 28/11/2021 | 300-2 v RennesLorient 0-2 Rennes | French Ligue 1 |
| 15 | 5/12/2021 | 300-1 v NantesLorient 0-1 Nantes | French Ligue 1 |
| 16 | 12/12/2021 | 301-4 v MetzMetz 4-1 Lorient | French Ligue 1 |
| 17 | 22/12/2021 | 301-1 v Paris St GermainLorient 1-1 Paris St Germain | French Ligue 1 |
| 18 | 16/1/2022 | 300-0 v AngersLorient 0-0 Angers | French Ligue 1 |
| 19 | 19/1/2022 | 301-3 v LilleLille 3-1 Lorient | French Ligue 1 |
| 20 | 23/1/2022 | 302-4 v NantesNantes 4-2 Lorient | French Ligue 1 |
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