| 1 | 9/8/2019 | 73-0 v MonacoMonaco 0-3 Lyon | French Ligue 1 |
| 2 | 16/8/2019 | 76-0 v AngersLyon 6-0 Angers | French Ligue 1 |
| 3 | 27/8/2019 | 70-1 v MontpellierMontpellier 1-0 Lyon | French Ligue 1 |
| 4 | 31/8/2019 | 71-1 v BordeauxLyon 1-1 Bordeaux | French Ligue 1 |
| 5 | 13/9/2019 | 72-2 v AmiensAmiens 2-2 Lyon | French Ligue 1 |
| 6 | 17/9/2019 | 71-1 v Zenit St PetersburgLyon 1-1 Zenit St Petersburg | UEFA Champions League Group G |
| 7 | 22/9/2019 | 70-1 v Paris St GermainLyon 0-1 Paris St Germain | French Ligue 1 |
| 8 | 25/9/2019 | 72-2 v BrestBrest 2-2 Lyon | French Ligue 1 |
| 9 | 28/9/2019 | 70-1 v NantesLyon 0-1 Nantes | French Ligue 1 |
| 10 | 2/10/2019 | 72-0 v RB LeipzigRB Leipzig 0-2 Lyon | UEFA Champions League Group G |
| 11 | 6/10/2019 | 70-1 v Saint ÉtienneSaint Étienne 1-0 Lyon | French Ligue 1 |
| 12 | 19/10/2019 | 70-0 v DijonLyon 0-0 Dijon | French Ligue 1 |
| 13 | 23/10/2019 | 71-2 v BenficaBenfica 2-1 Lyon | UEFA Champions League Group G |
| 14 | 26/10/2019 | 72-0 v MetzLyon 2-0 Metz | French Ligue 1 |
| 15 | 10/11/2019 | 71-2 v MarseilleMarseille 2-1 Lyon | French Ligue 1 |
| 16 | 23/11/2019 | 72-1 v NiceLyon 2-1 Nice | French Ligue 1 |
| 17 | 30/11/2019 | 72-1 v StrasbourgStrasbourg 1-2 Lyon | French Ligue 1 |
| 18 | 3/12/2019 | 70-1 v LilleLyon 0-1 Lille | French Ligue 1 |
| 19 | 6/12/2019 | 74-0 v NîmesNîmes 0-4 Lyon | French Ligue 1 |
| 20 | 10/12/2019 | 72-2 v RB LeipzigLyon 2-2 RB Leipzig | UEFA Champions League Group G |
