| 1 | Sat 17 Aug 2019 | 50-3 v SC FreiburgSC Freiburg 3-0 Mainz 05 | German Bundesliga |
| 2 | Sat 24 Aug 2019 | 51-3 v Borussia MönchengladbachMainz 05 1-3 Borussia Mönchengladbach | German Bundesliga |
| 3 | Sat 31 Aug 2019 | 51-6 v Bayern MunichBayern Munich 6-1 Mainz 05 | German Bundesliga |
| 4 | Sat 14 Sep 2019 | 52-1 v Hertha BerlinMainz 05 2-1 Hertha Berlin | German Bundesliga |
| 5 | Fri 20 Sep 2019 | 51-2 v FC Schalke 04FC Schalke 04 2-1 Mainz 05 | German Bundesliga |
| 6 | Sat 28 Sep 2019 | 50-1 v VfL WolfsburgMainz 05 0-1 VfL Wolfsburg | German Bundesliga |
| 7 | Sat 5 Oct 2019 | 52-1 v SC Paderborn 07SC Paderborn 07 1-2 Mainz 05 | German Bundesliga |
| 8 | Sat 19 Oct 2019 | 5 0-1 v Fortuna DüsseldorfFortuna Düsseldorf 1-0 Mainz 05 | German Bundesliga |
| 9 | Fri 25 Oct 2019 | 53-1 v 1. FC KölnMainz 05 3-1 1. FC Köln | German Bundesliga |
| 10 | Sat 2 Nov 2019 | 50-8 v RB LeipzigRB Leipzig 8-0 Mainz 05 | German Bundesliga |
| 11 | Sat 9 Nov 2019 | 52-3 v 1. FC Union BerlinMainz 05 2-3 1. FC Union Berlin | German Bundesliga |
| 12 | Sun 24 Nov 2019 | 55-1 v 1899 Hoffenheim1899 Hoffenheim 1-5 Mainz 05 | German Bundesliga |
| 13 | Mon 2 Dec 2019 | 52-1 v Eintracht FrankfurtMainz 05 2-1 Eintracht Frankfurt | German Bundesliga |
| 14 | Sat 7 Dec 2019 | 51-2 v FC AugsburgFC Augsburg 2-1 Mainz 05 | German Bundesliga |
| 15 | Sat 14 Dec 2019 | 50-4 v Borussia DortmundMainz 05 0-4 Borussia Dortmund | German Bundesliga |
| 16 | Tue 17 Dec 2019 | 55-0 v Werder BremenWerder Bremen 0-5 Mainz 05 | German Bundesliga |
| 17 | Sat 21 Dec 2019 | 50-1 v Bayer 04 LeverkusenMainz 05 0-1 Bayer 04 Leverkusen | German Bundesliga |
| 18 | Sat 18 Jan 2020 | 51-2 v SC FreiburgMainz 05 1-2 SC Freiburg | German Bundesliga |
| 19 | Sat 25 Jan 2020 | 51-3 v Borussia MönchengladbachBorussia Mönchengladbach 3-1 Mainz 05 | German Bundesliga |
| 20 | Sat 1 Feb 2020 | 5 1-3 v Bayern MunichMainz 05 1-3 Bayern Munich | German Bundesliga |
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