| 1 | 17/8/2019 | 0-3 v SC FreiburgSC Freiburg 3-0 Mainz 05 | German Bundesliga |
| 2 | 24/8/2019 | 1-3 v Borussia MönchengladbachMainz 05 1-3 Borussia Mönchengladbach | German Bundesliga |
| 3 | 31/8/2019 | 1-6 v Bayern MunichBayern Munich 6-1 Mainz 05 | German Bundesliga |
| 4 | 14/9/2019 | 2-1 v Hertha BerlinMainz 05 2-1 Hertha Berlin | German Bundesliga |
| 5 | 28/9/2019 | 0-1 v VfL WolfsburgMainz 05 0-1 VfL Wolfsburg | German Bundesliga |
| 6 | 5/10/2019 | 2-1 v SC Paderborn 07SC Paderborn 07 1-2 Mainz 05 | German Bundesliga |
| 7 | 19/10/2019 | 0-1 v Fortuna DüsseldorfFortuna Düsseldorf 1-0 Mainz 05 | German Bundesliga |
| 8 | 25/10/2019 | 3-1 v 1. FC KölnMainz 05 3-1 1. FC Köln | German Bundesliga |
| 9 | 2/11/2019 | 0-8 v RB LeipzigRB Leipzig 8-0 Mainz 05 | German Bundesliga |
| 10 | 24/11/2019 | 5-1 v 1899 Hoffenheim1899 Hoffenheim 1-5 Mainz 05 | German Bundesliga |
| 11 | 2/12/2019 | 2-1 v Eintracht FrankfurtMainz 05 2-1 Eintracht Frankfurt | German Bundesliga |
| 12 | 7/12/2019 | 1-2 v FC AugsburgFC Augsburg 2-1 Mainz 05 | German Bundesliga |
| 13 | 14/12/2019 | 0-4 v Borussia DortmundMainz 05 0-4 Borussia Dortmund | German Bundesliga |
| 14 | 17/12/2019 | 5-0 v Werder BremenWerder Bremen 0-5 Mainz 05 | German Bundesliga |
