| 1 | Sat 14 Aug 2021 | 115-1 v Leeds UnitedManchester United 5-1 Leeds United | Premier League |
| 2 | Sun 22 Aug 2021 | 111-1 v SouthamptonSouthampton 1-1 Manchester United | Premier League |
| 3 | Sun 29 Aug 2021 | 111-0 v Wolverhampton WanderersWolverhampton Wanderers 0-1 Manchester United | Premier League |
| 4 | Sat 11 Sep 2021 | 114-1 v Newcastle UnitedManchester United 4-1 Newcastle United | Premier League |
| 5 | Sun 19 Sep 2021 | 112-1 v West Ham UnitedWest Ham United 1-2 Manchester United | Premier League |
| 6 | Wed 22 Sep 2021 | 110-1 v West Ham UnitedManchester United 0-1 West Ham United | Carabao Cup Third Round |
| 7 | Sat 25 Sep 2021 | 110-1 v Aston VillaManchester United 0-1 Aston Villa | Premier League |
| 8 | Wed 29 Sep 2021 | 11 2-1 v VillarrealManchester United 2-1 Villarreal | UEFA Champions League Group F |
| 9 | Sat 2 Oct 2021 | 11 1-1 v EvertonManchester United 1-1 Everton | Premier League |
| 10 | Sat 16 Oct 2021 | 112-4 v Leicester CityLeicester City 4-2 Manchester United | Premier League |
| 11 | Wed 20 Oct 2021 | 113-2 v AtalantaManchester United 3-2 Atalanta | UEFA Champions League Group F |
| 12 | Sun 24 Oct 2021 | 110-5 v LiverpoolManchester United 0-5 Liverpool | Premier League |
| 13 | Tue 2 Nov 2021 | 112-2 v AtalantaAtalanta 2-2 Manchester United | UEFA Champions League Group F |
| 14 | Sat 6 Nov 2021 | 110-2 v Manchester CityManchester United 0-2 Manchester City | Premier League |
| 15 | Sun 5 Dec 2021 | 111-0 v Crystal PalaceManchester United 1-0 Crystal Palace | Premier League |
| 16 | Wed 8 Dec 2021 | 111-1 v Young BoysManchester United 1-1 Young Boys | UEFA Champions League Group F |
| 17 | Sat 11 Dec 2021 | 111-0 v Norwich CityNorwich City 0-1 Manchester United | Premier League |
| 18 | Mon 27 Dec 2021 | 111-1 v Newcastle UnitedNewcastle United 1-1 Manchester United | Premier League |
| 19 | Thu 30 Dec 2021 | 113-1 v BurnleyManchester United 3-1 Burnley | Premier League |
| 20 | Mon 3 Jan 2022 | 110-1 v Wolverhampton WanderersManchester United 0-1 Wolverhampton Wanderers | Premier League |
| 21 | Mon 10 Jan 2022 | 111-0 v Aston VillaManchester United 1-0 Aston Villa | Emirates FA Cup Third Round |
| 22 | Sat 15 Jan 2022 | 112-2 v Aston VillaAston Villa 2-2 Manchester United | Premier League |
| 23 | Wed 19 Jan 2022 | 113-1 v BrentfordBrentford 1-3 Manchester United | Premier League |
| 24 | Sat 22 Jan 2022 | 111-0 v West Ham UnitedManchester United 1-0 West Ham United | Premier League |
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