| 1 | Sun 8 Aug 2021 | 262-3 v MarseilleMontpellier 2-3 Marseille | French Ligue 1 |
| 2 | Sun 15 Aug 2021 | 26 3-3 v ReimsReims 3-3 Montpellier | French Ligue 1 |
| 3 | Sun 22 Aug 2021 | 263-1 v LorientMontpellier 3-1 Lorient | French Ligue 1 |
| 4 | Sun 29 Aug 2021 | 261-2 v LilleLille 2-1 Montpellier | French Ligue 1 |
| 5 | Sun 12 Sep 2021 | 262-0 v Saint ÉtienneMontpellier 2-0 Saint Étienne | French Ligue 1 |
| 6 | Sat 25 Sep 2021 | 260-2 v Paris St GermainParis St Germain 2-0 Montpellier | French Ligue 1 |
| 7 | Sat 20 Nov 2021 | 260-2 v RennesRennes 2-0 Montpellier | French Ligue 1 |
| 8 | Sat 11 Dec 2021 | 264-0 v BrestBrest 0-4 Montpellier | French Ligue 1 |
| 9 | Wed 22 Dec 2021 | 264-1 v AngersMontpellier 4-1 Angers | French Ligue 1 |
| 10 | Sun 20 Feb 2022 | 261-0 v LorientLorient 0-1 Montpellier | French Ligue 1 |
| 11 | Fri 25 Feb 2022 | 262-4 v RennesMontpellier 2-4 Rennes | French Ligue 1 |
| 12 | Sun 6 Mar 2022 | 260-2 v NantesNantes 2-0 Montpellier | French Ligue 1 |
| 13 | Sun 20 Mar 2022 | 262-0 v BordeauxBordeaux 0-2 Montpellier | French Ligue 1 |
| 14 | Sun 8 May 2022 | 261-2 v ClermontClermont 2-1 Montpellier | French Ligue 1 |
| 15 | Sat 14 May 2022 | 260-4 v Paris St GermainMontpellier 0-4 Paris St Germain | French Ligue 1 |
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