| 1 | Sat 14 Aug 2021 | 121-2 v Mansfield TownMansfield Town 2-1 Newport County | Sky Bet League Two |
| 2 | Sat 21 Aug 2021 | 121-0 v Tranmere RoversTranmere Rovers 0-1 Newport County | Sky Bet League Two |
| 3 | Sat 28 Aug 2021 | 120-3 v Salford CitySalford City 3-0 Newport County | Sky Bet League Two |
| 4 | Sat 4 Sep 2021 | 122-2 v Leyton OrientNewport County 2-2 Leyton Orient | Sky Bet League Two |
| 5 | Fri 10 Sep 2021 | 122-2 v Harrogate TownHarrogate Town 2-2 Newport County | Sky Bet League Two |
| 6 | Sat 18 Sep 2021 | 12 2-1 v WalsallNewport County 2-1 Walsall | Sky Bet League Two |
| 7 | Fri 24 Sep 2021 | 121-2 v BarrowBarrow 2-1 Newport County | Sky Bet League Two |
| 8 | Sat 2 Oct 2021 | 123-0 v Scunthorpe UnitedNewport County 3-0 Scunthorpe United | Sky Bet League Two |
| 9 | Sat 9 Oct 2021 | 120-0 v Bradford CityNewport County 0-0 Bradford City | Sky Bet League Two |
| 10 | Sat 16 Oct 2021 | 122-2 v Exeter CityExeter City 2-2 Newport County | Sky Bet League Two |
| 11 | Tue 19 Oct 2021 | 122-2 v Carlisle UnitedNewport County 2-2 Carlisle United | Sky Bet League Two |
| 12 | Sat 30 Oct 2021 | 125-0 v StevenageNewport County 5-0 Stevenage | Sky Bet League Two |
| 13 | Sat 6 Nov 2021 | 120-1 v MorecambeMorecambe 1-0 Newport County | Emirates FA Cup First Round |
| 14 | Tue 9 Nov 2021 | 120-1 v Swindon TownSwindon Town 1-0 Newport County | Papa John’s Trophy |
| 15 | Tue 23 Nov 2021 | 12 1-1 v Crawley TownCrawley Town 1-1 Newport County | Sky Bet League Two |
| 16 | Tue 7 Dec 2021 | 123-2 v Sutton UnitedNewport County 3-2 Sutton United | Sky Bet League Two |
| 17 | Sat 1 Jan 2022 | 123-3 v WalsallWalsall 3-3 Newport County | Sky Bet League Two |
| 18 | Tue 25 Jan 2022 | 121-0 v Leyton OrientLeyton Orient 0-1 Newport County | Sky Bet League Two |
| 19 | Sat 26 Feb 2022 | 124-2 v Tranmere RoversNewport County 4-2 Tranmere Rovers | Sky Bet League Two |
| 20 | Tue 1 Mar 2022 | 121-1 v Forest Green RoversNewport County 1-1 Forest Green Rovers | Sky Bet League Two |
| 21 | Sat 5 Mar 2022 | 121-0 v Bristol RoversNewport County 1-0 Bristol Rovers | Sky Bet League Two |
| 22 | Tue 15 Mar 2022 | 122-1 v Carlisle UnitedCarlisle United 1-2 Newport County | Sky Bet League Two |
| 23 | Sat 26 Mar 2022 | 120-0 v Bradford CityBradford City 0-0 Newport County | Sky Bet League Two |
| 24 | Sat 2 Apr 2022 | 120-1 v Exeter CityNewport County 0-1 Exeter City | Sky Bet League Two |
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