| 1 | Sat 29 Jan 2022 | 112-1 v BarrowNewport County 2-1 Barrow | Sky Bet League Two |
| 2 | Sat 5 Feb 2022 | 11 0-2 v Forest Green RoversForest Green Rovers 2-0 Newport County | Sky Bet League Two |
| 3 | Tue 8 Feb 2022 | 110-1 v Northampton TownNorthampton Town 1-0 Newport County | Sky Bet League Two |
| 4 | Sat 12 Feb 2022 | 113-3 v Oldham AthleticNewport County 3-3 Oldham Athletic | Sky Bet League Two |
| 5 | Sat 26 Feb 2022 | 114-2 v Tranmere RoversNewport County 4-2 Tranmere Rovers | Sky Bet League Two |
| 6 | Tue 1 Mar 2022 | 11 1-1 v Forest Green RoversNewport County 1-1 Forest Green Rovers | Sky Bet League Two |
| 7 | Sat 5 Mar 2022 | 111-0 v Bristol RoversNewport County 1-0 Bristol Rovers | Sky Bet League Two |
| 8 | Sat 12 Mar 2022 | 112-0 v StevenageStevenage 0-2 Newport County | Sky Bet League Two |
| 9 | Tue 15 Mar 2022 | 112-1 v Carlisle UnitedCarlisle United 1-2 Newport County | Sky Bet League Two |
| 10 | Fri 18 Mar 2022 | 112-3 v Hartlepool UnitedNewport County 2-3 Hartlepool United | Sky Bet League Two |
| 11 | Sat 26 Mar 2022 | 11 0-0 v Bradford CityBradford City 0-0 Newport County | Sky Bet League Two |
| 12 | Sat 2 Apr 2022 | 110-1 v Exeter CityNewport County 0-1 Exeter City | Sky Bet League Two |
| 13 | Sat 9 Apr 2022 | 111-0 v Swindon TownSwindon Town 0-1 Newport County | Sky Bet League Two |
| 14 | Fri 15 Apr 2022 | 111-2 v Crawley TownNewport County 1-2 Crawley Town | Sky Bet League Two |
| 15 | Mon 18 Apr 2022 | 110-1 v Sutton UnitedSutton United 1-0 Newport County | Sky Bet League Two |
| 16 | Fri 22 Apr 2022 | 111-2 v Colchester UnitedNewport County 1-2 Colchester United | Sky Bet League Two |
| 17 | Mon 2 May 2022 | 112-1 v Port ValePort Vale 1-2 Newport County | Sky Bet League Two |
| 18 | Sat 7 May 2022 | 110-2 v RochdaleNewport County 0-2 Rochdale | Sky Bet League Two |
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