| 1 | 11/7/2018 | 52-0 v UCDUCD 0-2 Oxford United | Friendly |
| 2 | 27/7/2018 | 50-1 v Milton Keynes DonsMilton Keynes Dons 1-0 Oxford United | Friendly |
| 3 | 4/8/2018 | 50-4 v BarnsleyBarnsley 4-0 Oxford United | Sky Bet League One |
| 4 | 11/8/2018 | 50-2 v Fleetwood TownOxford United 0-2 Fleetwood Town | Sky Bet League One |
| 5 | 18/8/2018 | 51-4 v PortsmouthPortsmouth 4-1 Oxford United | Sky Bet League One |
| 6 | 21/8/2018 | 52-3 v Accrington StanleyOxford United 2-3 Accrington Stanley | Sky Bet League One |
| 7 | 25/8/2018 | 5 3-1 v Burton AlbionOxford United 3-1 Burton Albion | Sky Bet League One |
| 8 | 1/9/2018 | 51-1 v SunderlandSunderland 1-1 Oxford United | Sky Bet League One |
| 9 | 9/9/2018 | 51-2 v Coventry CityOxford United 1-2 Coventry City | Sky Bet League One |
| 10 | 15/9/2018 | 50-0 v Wycombe WanderersWycombe Wanderers 0-0 Oxford United | Sky Bet League One |
| 11 | 22/9/2018 | 51-2 v WalsallOxford United 1-2 Walsall | Sky Bet League One |
| 12 | 25/9/2018 | 50-3 v Manchester CityOxford United 0-3 Manchester City | Carabao Cup Third Round |
| 13 | 29/9/2018 | 51-2 v AFC WimbledonAFC Wimbledon 2-1 Oxford United | Sky Bet League One |
| 14 | 2/10/2018 | 51-2 v Luton TownOxford United 1-2 Luton Town | Sky Bet League One |
| 15 | 6/10/2018 | 50-0 v Southend UnitedSouthend United 0-0 Oxford United | Sky Bet League One |
| 16 | 13/10/2018 | 52-0 v Plymouth ArgyleOxford United 2-0 Plymouth Argyle | Sky Bet League One |
| 17 | 20/10/2018 | 50-0 v Bristol RoversBristol Rovers 0-0 Oxford United | Sky Bet League One |
| 18 | 23/10/2018 | 5 1-1 v Charlton AthleticCharlton Athletic 1-1 Oxford United | Sky Bet League One |
| 19 | 27/10/2018 | 53-0 v Shrewsbury TownOxford United 3-0 Shrewsbury Town | Sky Bet League One |
| 20 | 3/11/2018 | 53-3 v Scunthorpe UnitedScunthorpe United 3-3 Oxford United | Sky Bet League One |
| 21 | 10/11/2018 | 50-0 v Forest Green RoversOxford United 0-0 Forest Green Rovers | Emirates FA Cup First Round |
| 22 | 17/11/2018 | 51-0 v GillinghamOxford United 1-0 Gillingham | Sky Bet League One |
| 23 | 20/11/2018 | 53-0 v Forest Green RoversForest Green Rovers 0-3 Oxford United | Emirates FA Cup First Round Replay |
| 24 | 27/11/2018 | 54-2 v RochdaleOxford United 4-2 Rochdale | Sky Bet League One |
| 25 | 1/12/2018 | 52-1 v Plymouth ArgylePlymouth Argyle 1-2 Oxford United | Emirates FA Cup Second Round |
| 26 | 8/12/2018 | 5 2-2 v Peterborough UnitedPeterborough United 2-2 Oxford United | Sky Bet League One |
| 27 | 15/12/2018 | 52-0 v BlackpoolOxford United 2-0 Blackpool | Sky Bet League One |
| 28 | 22/12/2018 | 52-2 v Doncaster RoversDoncaster Rovers 2-2 Oxford United | Sky Bet League One |
| 29 | 26/12/2018 | 50-1 v Southend UnitedOxford United 0-1 Southend United | Sky Bet League One |
| 30 | 29/12/2018 | 50-2 v Bristol RoversOxford United 0-2 Bristol Rovers | Sky Bet League One |
| 31 | 1/1/2019 | 5 0-3 v Plymouth ArgylePlymouth Argyle 3-0 Oxford United | Sky Bet League One |
| 32 | 8/1/2019 | 51-1 v Cheltenham TownCheltenham Town 1-1 Oxford United | Checkatrade Trophy Second Round |
| 33 | 12/1/2019 | 52-2 v Fleetwood TownFleetwood Town 2-2 Oxford United | Sky Bet League One |
| 34 | 19/1/2019 | 52-1 v PortsmouthOxford United 2-1 Portsmouth | Sky Bet League One |
| 35 | 22/1/2019 | 52-5 v BuryBury 5-2 Oxford United | Checkatrade Trophy Fourth Round |
| 36 | 29/1/2019 | 52-2 v BarnsleyOxford United 2-2 Barnsley | Sky Bet League One |
| 37 | 2/2/2019 | 50-0 v Burton AlbionBurton Albion 0-0 Oxford United | Sky Bet League One |
| 38 | 9/2/2019 | 51-1 v SunderlandOxford United 1-1 Sunderland | Sky Bet League One |
| 39 | 16/2/2019 | 50-1 v Peterborough UnitedOxford United 0-1 Peterborough United | Sky Bet League One |
| 40 | 19/2/2019 | 52-4 v Accrington StanleyAccrington Stanley 4-2 Oxford United | Sky Bet League One |
| 41 | 23/2/2019 | 51-0 v BlackpoolBlackpool 0-1 Oxford United | Sky Bet League One |
| 42 | 2/3/2019 | 52-1 v Scunthorpe UnitedOxford United 2-1 Scunthorpe United | Sky Bet League One |
| 43 | 9/3/2019 | 50-1 v GillinghamGillingham 1-0 Oxford United | Sky Bet League One |
| 44 | 12/3/2019 | 50-0 v RochdaleRochdale 0-0 Oxford United | Sky Bet League One |
| 45 | 16/3/2019 | 51-0 v Bradford CityOxford United 1-0 Bradford City | Sky Bet League One |
| 46 | 23/3/2019 | 51-0 v Coventry CityCoventry City 0-1 Oxford United | Sky Bet League One |
| 47 | 30/3/2019 | 52-1 v Wycombe WanderersOxford United 2-1 Wycombe Wanderers | Sky Bet League One |
| 48 | 6/4/2019 | 53-1 v WalsallWalsall 1-3 Oxford United | Sky Bet League One |
| 49 | 13/4/2019 | 50-0 v AFC WimbledonOxford United 0-0 AFC Wimbledon | Sky Bet League One |
| 50 | 19/4/2019 | 52-1 v Charlton AthleticOxford United 2-1 Charlton Athletic | Sky Bet League One |
| 51 | 22/4/2019 | 53-2 v Shrewsbury TownShrewsbury Town 2-3 Oxford United | Sky Bet League One |
| 52 | 27/4/2019 | 5 2-2 v Doncaster RoversOxford United 2-2 Doncaster Rovers | Sky Bet League One |
| 53 | 4/5/2019 | 51-3 v Luton TownLuton Town 3-1 Oxford United | Sky Bet League One |
