| 1 | Sun 13 Sep 2020 | 43-1 v FC GroningenFC Groningen 1-3 PSV Eindhoven | Dutch Eredivisie |
| 2 | Sun 27 Sep 2020 | 41-1 v Heracles AlmeloHeracles Almelo 1-1 PSV Eindhoven | Dutch Eredivisie |
| 3 | Thu 1 Oct 2020 | 42-0 v RosenborgRosenborg 0-2 PSV Eindhoven | Europa League Qualifying Play-off Round |
| 4 | Sun 4 Oct 2020 | 42-0 v Fortuna SittardPSV Eindhoven 2-0 Fortuna Sittard | Dutch Eredivisie |
| 5 | Thu 22 Oct 2020 | 41-2 v GranadaPSV Eindhoven 1-2 Granada | Europa League Group E |
| 6 | Sun 29 Nov 2020 | 41-0 v Sparta RotterdamPSV Eindhoven 1-0 Sparta Rotterdam | Dutch Eredivisie |
| 7 | Thu 10 Dec 2020 | 44-0 v Omonia NicosiaPSV Eindhoven 4-0 Omonia Nicosia | Europa League Group E |
| 8 | Sun 13 Dec 2020 | 42-1 v FC UtrechtPSV Eindhoven 2-1 FC Utrecht | Dutch Eredivisie |
| 9 | Sun 21 Feb 2021 | 43-1 v VitessePSV Eindhoven 3-1 Vitesse | Dutch Eredivisie |
| 10 | Thu 25 Feb 2021 | 42-1 v OlympiakosPSV Eindhoven 2-1 Olympiakos | Europa League Round of 32 |
| 11 | Sun 28 Feb 2021 | 41-1 v AjaxPSV Eindhoven 1-1 Ajax | Dutch Eredivisie |
| 12 | Sun 7 Mar 2021 | 4 3-1 v Fortuna SittardFortuna Sittard 1-3 PSV Eindhoven | Dutch Eredivisie |
| 13 | Sun 14 Mar 2021 | 4 1-1 v FeyenoordPSV Eindhoven 1-1 Feyenoord | Dutch Eredivisie |
| 14 | Sun 21 Mar 2021 | 40-2 v AZ AlkmaarAZ Alkmaar 2-0 PSV Eindhoven | Dutch Eredivisie |
| 15 | Sun 4 Apr 2021 | 43-0 v Heracles AlmeloPSV Eindhoven 3-0 Heracles Almelo | Dutch Eredivisie |
| 16 | Sun 11 Apr 2021 | 42-0 v VVV VenloVVV Venlo 0-2 PSV Eindhoven | Dutch Eredivisie |
| 17 | Sat 24 Apr 2021 | 41-0 v FC GroningenPSV Eindhoven 1-0 FC Groningen | Dutch Eredivisie |
| 18 | Sun 2 May 2021 | 4 2-2 v sc HeerenveenPSV Eindhoven 2-2 sc Heerenveen | Dutch Eredivisie |
| 19 | Sun 9 May 2021 | 42-0 v Willem IIWillem II 0-2 PSV Eindhoven | Dutch Eredivisie |
| 20 | Thu 13 May 2021 | 44-2 v PEC ZwollePSV Eindhoven 4-2 PEC Zwolle | Dutch Eredivisie |
| 21 | Sun 16 May 2021 | 41-1 v FC UtrechtFC Utrecht 1-1 PSV Eindhoven | Dutch Eredivisie |
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