| 1 | 19/9/2020 | 40-3 v Hellas VeronaHellas Verona 3-0 Roma | Italian Serie A |
| 2 | 3/10/2020 | 41-0 v UdineseUdinese 0-1 Roma | Italian Serie A |
| 3 | 18/10/2020 | 45-2 v BeneventoRoma 5-2 Benevento | Italian Serie A |
| 4 | 22/10/2020 | 42-1 v Young BoysYoung Boys 1-2 Roma | Europa League Group A |
| 5 | 26/10/2020 | 4 3-3 v AC MilanAC Milan 3-3 Roma | Italian Serie A |
| 6 | 29/10/2020 | 40-0 v CSKA SofiaRoma 0-0 CSKA Sofia | Europa League Group A |
| 7 | 1/11/2020 | 4 2-0 v FiorentinaRoma 2-0 Fiorentina | Italian Serie A |
| 8 | 5/11/2020 | 45-0 v CFR Cluj-NapocaRoma 5-0 CFR Cluj-Napoca | Europa League Group A |
| 9 | 8/11/2020 | 43-1 v GenoaGenoa 1-3 Roma | Italian Serie A |
| 10 | 22/11/2020 | 43-0 v ParmaRoma 3-0 Parma | Italian Serie A |
| 11 | 26/11/2020 | 42-0 v CFR Cluj-NapocaCFR Cluj-Napoca 0-2 Roma | Europa League Group A |
| 12 | 29/11/2020 | 4 0-4 v NapoliNapoli 4-0 Roma | Italian Serie A |
| 13 | 3/12/2020 | 43-1 v Young BoysRoma 3-1 Young Boys | Europa League Group A |
| 14 | 6/12/2020 | 40-0 v SassuoloRoma 0-0 Sassuolo | Italian Serie A |
| 15 | 13/12/2020 | 45-1 v BolognaBologna 1-5 Roma | Italian Serie A |
| 16 | 20/12/2020 | 41-4 v AtalantaAtalanta 4-1 Roma | Italian Serie A |
| 17 | 23/12/2020 | 4 3-2 v CagliariRoma 3-2 Cagliari | Italian Serie A |
| 18 | 3/1/2021 | 41-0 v SampdoriaRoma 1-0 Sampdoria | Italian Serie A |
| 19 | 6/1/2021 | 43-1 v CrotoneCrotone 1-3 Roma | Italian Serie A |
| 20 | 10/1/2021 | 42-2 v Inter MilanRoma 2-2 Inter Milan | Italian Serie A |
| 21 | 15/1/2021 | 40-3 v LazioLazio 3-0 Roma | Italian Serie A |
| 22 | 23/1/2021 | 44-3 v SpeziaRoma 4-3 Spezia | Italian Serie A |
| 23 | 31/1/2021 | 43-1 v Hellas VeronaRoma 3-1 Hellas Verona | Italian Serie A |
| 24 | 6/2/2021 | 40-2 v JuventusJuventus 2-0 Roma | Italian Serie A |
| 25 | 14/2/2021 | 43-0 v UdineseRoma 3-0 Udinese | Italian Serie A |
| 26 | 18/2/2021 | 42-0 v Sporting BragaSporting Braga 0-2 Roma | Europa League Round of 32 |
| 27 | 25/2/2021 | 43-1 v Sporting BragaRoma 3-1 Sporting Braga | Europa League Round of 32 |
| 28 | 28/2/2021 | 41-2 v AC MilanRoma 1-2 AC Milan | Italian Serie A |
| 29 | 3/3/2021 | 42-1 v FiorentinaFiorentina 1-2 Roma | Italian Serie A |
| 30 | 7/3/2021 | 41-0 v GenoaRoma 1-0 Genoa | Italian Serie A |
| 31 | 11/3/2021 | 4 3-0 v Shakhtar DonetskRoma 3-0 Shakhtar Donetsk | Europa League Round of 16 |
| 32 | 14/3/2021 | 40-2 v ParmaParma 2-0 Roma | Italian Serie A |
| 33 | 18/3/2021 | 42-1 v Shakhtar DonetskShakhtar Donetsk 1-2 Roma | Europa League Round of 16 |
| 34 | 21/3/2021 | 4 0-2 v NapoliRoma 0-2 Napoli | Italian Serie A |
| 35 | 3/4/2021 | 4 2-2 v SassuoloSassuolo 2-2 Roma | Italian Serie A |
| 36 | 8/4/2021 | 4 2-1 v AjaxAjax 1-2 Roma | Europa League Quarter Final |
| 37 | 15/4/2021 | 4 1-1 v AjaxRoma 1-1 Ajax | Europa League Quarter Final |
| 38 | 18/4/2021 | 41-3 v TorinoTorino 3-1 Roma | Italian Serie A |
| 39 | 22/4/2021 | 41-1 v AtalantaRoma 1-1 Atalanta | Italian Serie A |
| 40 | 25/4/2021 | 4 2-3 v CagliariCagliari 3-2 Roma | Italian Serie A |
| 41 | 29/4/2021 | 42-6 v Manchester UnitedManchester United 6-2 Roma | Europa League Semi Final |
| 42 | 2/5/2021 | 4 0-2 v SampdoriaSampdoria 2-0 Roma | Italian Serie A |
| 43 | 6/5/2021 | 4 3-2 v Manchester UnitedRoma 3-2 Manchester United | Europa League Semi Final |
| 44 | 9/5/2021 | 4 5-0 v CrotoneRoma 5-0 Crotone | Italian Serie A |
| 45 | 12/5/2021 | 41-3 v Inter MilanInter Milan 3-1 Roma | Italian Serie A |
| 46 | 15/5/2021 | 42-0 v LazioRoma 2-0 Lazio | Italian Serie A |
| 47 | 23/5/2021 | 42-2 v SpeziaSpezia 2-2 Roma | Italian Serie A |
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