| 1 | Sat 7 Aug 2021 | 181-1 v Leyton OrientSalford City 1-1 Leyton Orient | Sky Bet League Two |
| 2 | Sat 14 Aug 2021 | 18 0-0 v Sutton UnitedSalford City 0-0 Sutton United | Sky Bet League Two |
| 3 | Tue 17 Aug 2021 | 181-2 v Crawley TownCrawley Town 2-1 Salford City | Sky Bet League Two |
| 4 | Sat 21 Aug 2021 | 180-1 v Swindon TownSalford City 0-1 Swindon Town | Sky Bet League Two |
| 5 | Sat 28 Aug 2021 | 183-0 v Newport CountySalford City 3-0 Newport County | Sky Bet League Two |
| 6 | Sat 4 Sep 2021 | 181-2 v Carlisle UnitedCarlisle United 2-1 Salford City | Sky Bet League Two |
| 7 | Sat 11 Sep 2021 | 181-0 v Bradford CitySalford City 1-0 Bradford City | Sky Bet League Two |
| 8 | Sat 9 Oct 2021 | 181-2 v WalsallWalsall 2-1 Salford City | Sky Bet League Two |
| 9 | Sat 16 Oct 2021 | 182-0 v Hartlepool UnitedSalford City 2-0 Hartlepool United | Sky Bet League Two |
| 10 | Tue 19 Oct 2021 | 180-0 v RochdaleSalford City 0-0 Rochdale | Sky Bet League Two |
| 11 | Mon 8 Nov 2021 | 181-0 v Dagenham & RedbridgeDagenham & Redbridge 0-1 Salford City | Emirates FA Cup First Round |
| 12 | Sat 13 Nov 2021 | 181-1 v Scunthorpe UnitedScunthorpe United 1-1 Salford City | Sky Bet League Two |
| 13 | Sat 27 Nov 2021 | 182-0 v Oldham AthleticSalford City 2-0 Oldham Athletic | Sky Bet League Two |
| 14 | Sat 11 Dec 2021 | 181-2 v Mansfield TownMansfield Town 2-1 Salford City | Sky Bet League Two |
| 15 | Sat 18 Dec 2021 | 181-0 v StevenageSalford City 1-0 Stevenage | Sky Bet League Two |
| 16 | Tue 11 Jan 2022 | 181-1 v Tranmere RoversSalford City 1-1 Tranmere Rovers | Sky Bet League Two |
| 17 | Tue 18 Jan 2022 | 181-0 v Port ValePort Vale 0-1 Salford City | Sky Bet League Two |
| 18 | Sat 22 Jan 2022 | 180-3 v Colchester UnitedSalford City 0-3 Colchester United | Sky Bet League Two |
| 19 | Tue 25 Jan 2022 | 182-0 v BarrowBarrow 0-2 Salford City | Sky Bet League Two |
| 20 | Sat 29 Jan 2022 | 180-1 v Northampton TownNorthampton Town 1-0 Salford City | Sky Bet League Two |
| 21 | Tue 1 Feb 2022 | 182-1 v Carlisle UnitedSalford City 2-1 Carlisle United | Sky Bet League Two |
| 22 | Tue 8 Feb 2022 | 180-0 v Sutton UnitedSutton United 0-0 Salford City | Sky Bet League Two |
| 23 | Sat 12 Feb 2022 | 182-0 v Leyton OrientLeyton Orient 0-2 Salford City | Sky Bet League Two |
| 24 | Sat 26 Feb 2022 | 182-1 v Swindon TownSwindon Town 1-2 Salford City | Sky Bet League Two |
| 25 | Sat 5 Mar 2022 | 181-1 v Forest Green RoversSalford City 1-1 Forest Green Rovers | Sky Bet League Two |
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