| 1 | Tue 17 Aug 2021 | 71-2 v Crawley TownCrawley Town 2-1 Salford City | Sky Bet League Two |
| 2 | Sat 21 Aug 2021 | 70-1 v Swindon TownSalford City 0-1 Swindon Town | Sky Bet League Two |
| 3 | Sat 28 Aug 2021 | 73-0 v Newport CountySalford City 3-0 Newport County | Sky Bet League Two |
| 4 | Sat 11 Sep 2021 | 71-0 v Bradford CitySalford City 1-0 Bradford City | Sky Bet League Two |
| 5 | Sat 18 Sep 2021 | 70-2 v Tranmere RoversTranmere Rovers 2-0 Salford City | Sky Bet League Two |
| 6 | Sat 25 Sep 2021 | 72-2 v Northampton TownSalford City 2-2 Northampton Town | Sky Bet League Two |
| 7 | Sat 2 Oct 2021 | 72-0 v Colchester UnitedColchester United 0-2 Salford City | Sky Bet League Two |
| 8 | Sat 16 Oct 2021 | 72-0 v Hartlepool UnitedSalford City 2-0 Hartlepool United | Sky Bet League Two |
| 9 | Tue 19 Oct 2021 | 70-0 v RochdaleSalford City 0-0 Rochdale | Sky Bet League Two |
| 10 | Sat 23 Oct 2021 | 71-3 v Forest Green RoversForest Green Rovers 3-1 Salford City | Sky Bet League Two |
| 11 | Sat 20 Nov 2021 | 72-0 v Harrogate TownHarrogate Town 0-2 Salford City | Sky Bet League Two |
| 12 | Tue 23 Nov 2021 | 71-1 v Bristol RoversSalford City 1-1 Bristol Rovers | Sky Bet League Two |
| 13 | Sun 5 Dec 2021 | 70-2 v ChesterfieldSalford City 0-2 Chesterfield | Emirates FA Cup Second Round |
| 14 | Sat 11 Dec 2021 | 71-2 v Mansfield TownMansfield Town 2-1 Salford City | Sky Bet League Two |
| 15 | Sat 18 Dec 2021 | 71-0 v StevenageSalford City 1-0 Stevenage | Sky Bet League Two |
| 16 | Sat 8 Jan 2022 | 72-0 v Newport CountyNewport County 0-2 Salford City | Sky Bet League Two |
| 17 | Tue 11 Jan 2022 | 7 1-1 v Tranmere RoversSalford City 1-1 Tranmere Rovers | Sky Bet League Two |
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