| 1 | 7/8/2021 | 131-3 v SV Zulte WaregemSint-Truidense VV 1-3 SV Zulte Waregem | Belgian First Division A |
| 2 | 14/8/2021 | 131-2 v KAS EupenKAS Eupen 2-1 Sint-Truidense VV | Belgian First Division A |
| 3 | 21/8/2021 | 130-2 v KV KortrijkSint-Truidense VV 0-2 KV Kortrijk | Belgian First Division A |
| 4 | 28/8/2021 | 131-0 v Cercle BruggeCercle Brugge 0-1 Sint-Truidense VV | Belgian First Division A |
| 5 | 13/9/2021 | 131-0 v Germinal BeerschotGerminal Beerschot 0-1 Sint-Truidense VV | Belgian First Division A |
| 6 | 19/9/2021 | 131-2 v KRC GenkSint-Truidense VV 1-2 KRC Genk | Belgian First Division A |
| 7 | 25/9/2021 | 132-1 v Standard LiègeStandard Liège 1-2 Sint-Truidense VV | Belgian First Division A |
| 8 | 2/10/2021 | 13 1-1 v KV OostendeSint-Truidense VV 1-1 KV Oostende | Belgian First Division A |
| 9 | 17/10/2021 | 132-2 v RSC AnderlechtSint-Truidense VV 2-2 RSC Anderlecht | Belgian First Division A |
| 10 | 24/10/2021 | 131-4 v Oud-Heverlee LeuvenOud-Heverlee Leuven 4-1 Sint-Truidense VV | Belgian First Division A |
| 11 | 30/10/2021 | 131-2 v Club BruggeSint-Truidense VV 1-2 Club Brugge | Belgian First Division A |
| 12 | 6/11/2021 | 131-0 v MechelenMechelen 0-1 Sint-Truidense VV | Belgian First Division A |
| 13 | 21/11/2021 | 132-1 v Royal AntwerpSint-Truidense VV 2-1 Royal Antwerp | Belgian First Division A |
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