| 1 | Sat 4 Aug 2018 | 200-3 v Borussia MönchengladbachSouthampton 0-3 Borussia Mönchengladbach | Friendly |
| 2 | Sun 12 Aug 2018 | 200-0 v BurnleySouthampton 0-0 Burnley | Premier League |
| 3 | Sat 18 Aug 2018 | 201-2 v EvertonEverton 2-1 Southampton | Premier League |
| 4 | Tue 28 Aug 2018 | 201-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-1 Southampton | Carabao Cup Second Round |
| 5 | Mon 17 Sep 2018 | 202-2 v Brighton & Hove AlbionSouthampton 2-2 Brighton & Hove Albion | Premier League |
| 6 | Sat 29 Sep 2018 | 200-2 v Wolverhampton WanderersWolverhampton Wanderers 2-0 Southampton | Premier League |
| 7 | Tue 2 Oct 2018 | 201-1 v EvertonEverton 1-1 Southampton | Carabao Cup Third Round |
| 8 | Sun 7 Oct 2018 | 200-3 v ChelseaSouthampton 0-3 Chelsea | Premier League |
| 9 | Sat 20 Oct 2018 | 200-0 v AFC BournemouthAFC Bournemouth 0-0 Southampton | Premier League |
| 10 | Sat 27 Oct 2018 | 200-0 v Newcastle UnitedSouthampton 0-0 Newcastle United | Premier League |
| 11 | Sat 10 Nov 2018 | 201-1 v WatfordSouthampton 1-1 Watford | Premier League |
| 12 | Sat 24 Nov 2018 | 202-3 v FulhamFulham 3-2 Southampton | Premier League |
| 13 | Tue 27 Nov 2018 | 200-0 v Leicester CityLeicester City 0-0 Southampton | Carabao Cup Fourth Round |
| 14 | Sat 1 Dec 2018 | 202-2 v Manchester UnitedSouthampton 2-2 Manchester United | Premier League |
| 15 | Wed 5 Dec 2018 | 201-3 v Tottenham HotspurTottenham Hotspur 3-1 Southampton | Premier League |
| 16 | Sat 8 Dec 2018 | 200-1 v Cardiff CityCardiff City 1-0 Southampton | Premier League |
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