| 1 | Sat 4 Aug 2018 | 330-3 v Borussia MönchengladbachSouthampton 0-3 Borussia Mönchengladbach | Friendly |
| 2 | Tue 28 Aug 2018 | 331-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-1 Southampton | Carabao Cup Second Round |
| 3 | Sat 1 Sep 2018 | 332-0 v Crystal PalaceCrystal Palace 0-2 Southampton | Premier League |
| 4 | Sat 22 Sep 2018 | 330-3 v LiverpoolLiverpool 3-0 Southampton | Premier League |
| 5 | Tue 2 Oct 2018 | 331-1 v EvertonEverton 1-1 Southampton | Carabao Cup Third Round |
| 6 | Sat 24 Nov 2018 | 332-3 v FulhamFulham 3-2 Southampton | Premier League |
| 7 | Tue 27 Nov 2018 | 330-0 v Leicester CityLeicester City 0-0 Southampton | Carabao Cup Fourth Round |
| 8 | Wed 5 Dec 2018 | 331-3 v Tottenham HotspurTottenham Hotspur 3-1 Southampton | Premier League |
| 9 | Sat 8 Dec 2018 | 330-1 v Cardiff CityCardiff City 1-0 Southampton | Premier League |
| 10 | Sun 16 Dec 2018 | 333-2 v ArsenalSouthampton 3-2 Arsenal | Premier League |
| 11 | Sat 22 Dec 2018 | 333-1 v Huddersfield TownHuddersfield Town 1-3 Southampton | Premier League |
| 12 | Thu 27 Dec 2018 | 33 1-2 v West Ham UnitedSouthampton 1-2 West Ham United | Premier League |
| 13 | Sun 30 Dec 2018 | 331-3 v Manchester CitySouthampton 1-3 Manchester City | Premier League |
| 14 | Sat 5 Jan 2019 | 332-2 v Derby CountyDerby County 2-2 Southampton | Emirates FA Cup Third Round |
| 15 | Sat 12 Jan 2019 | 332-1 v Leicester CityLeicester City 1-2 Southampton | Premier League |
| 16 | Wed 16 Jan 2019 | 332-2 v Derby CountySouthampton 2-2 Derby County | Emirates FA Cup Third Round Replay |
| 17 | Sat 19 Jan 2019 | 332-1 v EvertonSouthampton 2-1 Everton | Premier League |
| 18 | Wed 30 Jan 2019 | 331-1 v Crystal PalaceSouthampton 1-1 Crystal Palace | Premier League |
| 19 | Sat 2 Feb 2019 | 33 1-1 v BurnleyBurnley 1-1 Southampton | Premier League |
| 20 | Sun 24 Feb 2019 | 330-2 v ArsenalArsenal 2-0 Southampton | Premier League |
| 21 | Sat 27 Apr 2019 | 333-3 v AFC BournemouthSouthampton 3-3 AFC Bournemouth | Premier League |
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