| 1 | 4/1/2021 | 721-0 v LiverpoolSouthampton 1-0 Liverpool | Premier League |
| 2 | 16/1/2021 | 720-2 v Leicester CityLeicester City 2-0 Southampton | Premier League |
| 3 | 19/1/2021 | 72 2-0 v Shrewsbury TownSouthampton 2-0 Shrewsbury Town | Emirates FA Cup Third Round |
| 4 | 23/1/2021 | 721-0 v ArsenalSouthampton 1-0 Arsenal | Emirates FA Cup Fourth Round |
| 5 | 26/1/2021 | 721-3 v ArsenalSouthampton 1-3 Arsenal | Premier League |
| 6 | 2/2/2021 | 720-9 v Manchester UnitedManchester United 9-0 Southampton | Premier League |
| 7 | 6/2/2021 | 722-3 v Newcastle UnitedNewcastle United 3-2 Southampton | Premier League |
| 8 | 11/2/2021 | 722-0 v Wolverhampton WanderersWolverhampton Wanderers 0-2 Southampton | Emirates FA Cup Fifth Round |
| 9 | 14/2/2021 | 721-2 v Wolverhampton WanderersSouthampton 1-2 Wolverhampton Wanderers | Premier League |
| 10 | 20/2/2021 | 721-1 v ChelseaSouthampton 1-1 Chelsea | Premier League |
| 11 | 23/2/2021 | 720-3 v Leeds UnitedLeeds United 3-0 Southampton | Premier League |
| 12 | 1/3/2021 | 720-1 v EvertonEverton 1-0 Southampton | Premier League |
| 13 | 6/3/2021 | 722-0 v Sheffield UnitedSheffield United 0-2 Southampton | Premier League |
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