| 1 | Sat 11 Sep 2021 | 430-0 v Dundee UnitedSt Mirren 0-0 Dundee United | Cinch Premiership |
| 2 | Sat 18 Sep 2021 | 432-2 v HibernianHibernian 2-2 St Mirren | Cinch Premiership |
| 3 | Sun 26 Sep 2021 | 433-2 v AberdeenSt Mirren 3-2 Aberdeen | Cinch Premiership |
| 4 | Sat 2 Oct 2021 | 431-0 v LivingstonLivingston 0-1 St Mirren | Cinch Premiership |
| 5 | Sat 16 Oct 2021 | 433-2 v Ross CountyRoss County 2-3 St Mirren | Cinch Premiership |
| 6 | Sun 24 Oct 2021 | 431-2 v RangersSt Mirren 1-2 Rangers | Cinch Premiership |
| 7 | Wed 27 Oct 2021 | 432-2 v MotherwellMotherwell 2-2 St Mirren | Cinch Premiership |
| 8 | Sat 30 Oct 2021 | 430-1 v DundeeSt Mirren 0-1 Dundee | Cinch Premiership |
| 9 | Sat 6 Nov 2021 | 430-0 v St JohnstoneSt Johnstone 0-0 St Mirren | Cinch Premiership |
| 10 | Sat 20 Nov 2021 | 431-1 v LivingstonSt Mirren 1-1 Livingston | Cinch Premiership |
| 11 | Sat 27 Nov 2021 | 430-2 v Heart of MidlothianHeart of Midlothian 2-0 St Mirren | Cinch Premiership |
| 12 | Wed 1 Dec 2021 | 43 0-0 v Ross CountySt Mirren 0-0 Ross County | Cinch Premiership |
| 13 | Sat 4 Dec 2021 | 431-4 v AberdeenAberdeen 4-1 St Mirren | Cinch Premiership |
| 14 | Sat 11 Dec 2021 | 431-1 v HibernianSt Mirren 1-1 Hibernian | Cinch Premiership |
| 15 | Tue 18 Jan 2022 | 432-1 v Dundee UnitedDundee United 1-2 St Mirren | Cinch Premiership |
| 16 | Tue 25 Jan 2022 | 431-0 v AberdeenSt Mirren 1-0 Aberdeen | Cinch Premiership |
| 17 | Tue 1 Feb 2022 | 431-1 v MotherwellSt Mirren 1-1 Motherwell | Cinch Premiership |
| 18 | Sat 5 Feb 2022 | 431-0 v HibernianHibernian 0-1 St Mirren | Cinch Premiership |
| 19 | Wed 9 Feb 2022 | 432-1 v St JohnstoneSt Mirren 2-1 St Johnstone | Cinch Premiership |
| 20 | Sat 19 Feb 2022 | 431-1 v LivingstonLivingston 1-1 St Mirren | Cinch Premiership |
| 21 | Sat 26 Feb 2022 | 43 0-2 v Heart of MidlothianSt Mirren 0-2 Heart of Midlothian | Cinch Premiership |
| 22 | Wed 9 Mar 2022 | 43 1-0 v DundeeDundee 0-1 St Mirren | Cinch Premiership |
| 23 | Sat 12 Mar 2022 | 432-4 v Heart of MidlothianHeart of Midlothian 4-2 St Mirren | William Hill Scottish Cup Quarter Final |
| 24 | Sat 19 Mar 2022 | 431-2 v Dundee UnitedSt Mirren 1-2 Dundee United | Cinch Premiership |
| 25 | Sat 2 Apr 2022 | 432-4 v MotherwellMotherwell 4-2 St Mirren | Cinch Premiership |
| 26 | Sun 10 Apr 2022 | 430-4 v RangersSt Mirren 0-4 Rangers | Cinch Premiership |
| 27 | Sat 23 Apr 2022 | 430-1 v HibernianSt Mirren 0-1 Hibernian | Cinch Premiership |
| 28 | Sat 30 Apr 2022 | 431-0 v St JohnstoneSt Johnstone 0-1 St Mirren | Cinch Premiership |
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