| 1 | Sat 5 Feb 2022 | 3-1 v Brighton & Hove AlbionTottenham Hotspur 3-1 Brighton & Hove Albion | Emirates FA Cup Fourth Round |
| 2 | Wed 9 Feb 2022 | 302-3 v SouthamptonTottenham Hotspur 2-3 Southampton | Premier League |
| 3 | Sun 13 Feb 2022 | 30 0-2 v Wolverhampton WanderersTottenham Hotspur 0-2 Wolverhampton Wanderers | Premier League |
| 4 | Sat 19 Feb 2022 | 303-2 v Manchester CityManchester City 2-3 Tottenham Hotspur | Premier League |
| 5 | Wed 23 Feb 2022 | 300-1 v BurnleyBurnley 1-0 Tottenham Hotspur | Premier League |
| 6 | Mon 7 Mar 2022 | 305-0 v EvertonTottenham Hotspur 5-0 Everton | Premier League |
| 7 | Sat 12 Mar 2022 | 302-3 v Manchester UnitedManchester United 3-2 Tottenham Hotspur | Premier League |
| 8 | Wed 16 Mar 2022 | 302-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-2 Tottenham Hotspur | Premier League |
| 9 | Sun 20 Mar 2022 | 303-1 v West Ham UnitedTottenham Hotspur 3-1 West Ham United | Premier League |
| 10 | Sun 3 Apr 2022 | 30 5-1 v Newcastle UnitedTottenham Hotspur 5-1 Newcastle United | Premier League |
| 11 | Sat 9 Apr 2022 | 304-0 v Aston VillaAston Villa 0-4 Tottenham Hotspur | Premier League |
| 12 | Sat 16 Apr 2022 | 30 0-1 v Brighton & Hove AlbionTottenham Hotspur 0-1 Brighton & Hove Albion | Premier League |
| 13 | Sat 23 Apr 2022 | 30 0-0 v BrentfordBrentford 0-0 Tottenham Hotspur | Premier League |
| 14 | Sun 1 May 2022 | 30 3-1 v Leicester CityTottenham Hotspur 3-1 Leicester City | Premier League |
| 15 | Sat 7 May 2022 | 301-1 v LiverpoolLiverpool 1-1 Tottenham Hotspur | Premier League |
| 16 | Thu 12 May 2022 | 303-0 v ArsenalTottenham Hotspur 3-0 Arsenal | Premier League |
| 17 | Sun 15 May 2022 | 301-0 v BurnleyTottenham Hotspur 1-0 Burnley | Premier League |
| 18 | Sun 22 May 2022 | 305-0 v Norwich CityNorwich City 0-5 Tottenham Hotspur | Premier League |
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