| 1 | Sat 21 Jul 2018 | 40-2 v Havant & WaterloovilleHavant & Waterlooville 2-0 Wycombe Wanderers | Friendly |
| 2 | Sat 11 Aug 2018 | 4 0-3 v Doncaster RoversDoncaster Rovers 3-0 Wycombe Wanderers | Sky Bet League One |
| 3 | Tue 14 Aug 2018 | 41-1 v Northampton TownWycombe Wanderers 1-1 Northampton Town | Carabao Cup First Round |
| 4 | Sat 18 Aug 2018 | 41-2 v Bristol RoversWycombe Wanderers 1-2 Bristol Rovers | Sky Bet League One |
| 5 | Tue 21 Aug 2018 | 41-1 v Plymouth ArgylePlymouth Argyle 1-1 Wycombe Wanderers | Sky Bet League One |
| 6 | Sat 25 Aug 2018 | 4 2-1 v Bradford CityBradford City 1-2 Wycombe Wanderers | Sky Bet League One |
| 7 | Sat 1 Sep 2018 | 41-1 v Luton TownWycombe Wanderers 1-1 Luton Town | Sky Bet League One |
| 8 | Sat 8 Sep 2018 | 42-3 v Charlton AthleticCharlton Athletic 3-2 Wycombe Wanderers | Sky Bet League One |
| 9 | Sat 15 Sep 2018 | 4 0-0 v Oxford UnitedWycombe Wanderers 0-0 Oxford United | Sky Bet League One |
| 10 | Sat 22 Sep 2018 | 42-2 v PortsmouthPortsmouth 2-2 Wycombe Wanderers | Sky Bet League One |
| 11 | Tue 25 Sep 2018 | 4 3-4 v Norwich CityWycombe Wanderers 3-4 Norwich City | Carabao Cup Third Round |
| 12 | Sat 29 Sep 2018 | 42-3 v Southend UnitedWycombe Wanderers 2-3 Southend United | Sky Bet League One |
| 13 | Tue 2 Oct 2018 | 41-1 v Fleetwood TownFleetwood Town 1-1 Wycombe Wanderers | Sky Bet League One |
| 14 | Sat 6 Oct 2018 | 42-1 v Burton AlbionWycombe Wanderers 2-1 Burton Albion | Sky Bet League One |
| 15 | Sat 13 Oct 2018 | 4 0-1 v Coventry CityCoventry City 1-0 Wycombe Wanderers | Sky Bet League One |
| 16 | Sat 20 Oct 2018 | 4 3-2 v Scunthorpe UnitedWycombe Wanderers 3-2 Scunthorpe United | Sky Bet League One |
| 17 | Sat 27 Oct 2018 | 42-3 v WalsallWalsall 3-2 Wycombe Wanderers | Sky Bet League One |
| 18 | Sat 3 Nov 2018 | 4 1-0 v Peterborough UnitedWycombe Wanderers 1-0 Peterborough United | Sky Bet League One |
| 19 | Tue 6 Nov 2018 | 40-3 v Oxford UnitedWycombe Wanderers 0-3 Oxford United | Checkatrade Trophy Southern Group F |
| 20 | Sat 10 Nov 2018 | 40-2 v Luton TownLuton Town 2-0 Wycombe Wanderers | Emirates FA Cup First Round |
| 21 | Sat 17 Nov 2018 | 41-1 v SunderlandSunderland 1-1 Wycombe Wanderers | Sky Bet League One |
| 22 | Sat 24 Nov 2018 | 43-2 v Shrewsbury TownWycombe Wanderers 3-2 Shrewsbury Town | Sky Bet League One |
| 23 | Tue 27 Nov 2018 | 42-1 v Accrington StanleyAccrington Stanley 1-2 Wycombe Wanderers | Sky Bet League One |
| 24 | Sat 8 Dec 2018 | 41-0 v BarnsleyWycombe Wanderers 1-0 Barnsley | Sky Bet League One |
| 25 | Sat 15 Dec 2018 | 42-2 v GillinghamGillingham 2-2 Wycombe Wanderers | Sky Bet League One |
| 26 | Sat 22 Dec 2018 | 41-2 v AFC WimbledonWycombe Wanderers 1-2 AFC Wimbledon | Sky Bet League One |
| 27 | Wed 26 Dec 2018 | 41-3 v Burton AlbionBurton Albion 3-1 Wycombe Wanderers | Sky Bet League One |
| 28 | Sat 29 Dec 2018 | 40-1 v Scunthorpe UnitedScunthorpe United 1-0 Wycombe Wanderers | Sky Bet League One |
| 29 | Tue 1 Jan 2019 | 40-2 v Coventry CityWycombe Wanderers 0-2 Coventry City | Sky Bet League One |
| 30 | Sat 12 Jan 2019 | 4 3-2 v Doncaster RoversWycombe Wanderers 3-2 Doncaster Rovers | Sky Bet League One |
| 31 | Sat 19 Jan 2019 | 41-0 v Bristol RoversBristol Rovers 0-1 Wycombe Wanderers | Sky Bet League One |
| 32 | Sat 26 Jan 2019 | 41-0 v Plymouth ArgyleWycombe Wanderers 1-0 Plymouth Argyle | Sky Bet League One |
| 33 | Tue 29 Jan 2019 | 42-2 v BlackpoolBlackpool 2-2 Wycombe Wanderers | Sky Bet League One |
| 34 | Sat 2 Feb 2019 | 40-0 v Bradford CityWycombe Wanderers 0-0 Bradford City | Sky Bet League One |
| 35 | Sat 9 Feb 2019 | 40-3 v Luton TownLuton Town 3-0 Wycombe Wanderers | Sky Bet League One |
| 36 | Sat 16 Feb 2019 | 41-2 v BarnsleyBarnsley 2-1 Wycombe Wanderers | Sky Bet League One |
| 37 | Sat 23 Feb 2019 | 40-1 v GillinghamWycombe Wanderers 0-1 Gillingham | Sky Bet League One |
| 38 | Sat 2 Mar 2019 | 42-4 v Peterborough UnitedPeterborough United 4-2 Wycombe Wanderers | Sky Bet League One |
| 39 | Sat 9 Mar 2019 | 41-1 v SunderlandWycombe Wanderers 1-1 Sunderland | Sky Bet League One |
| 40 | Sat 16 Mar 2019 | 41-2 v Shrewsbury TownShrewsbury Town 2-1 Wycombe Wanderers | Sky Bet League One |
| 41 | Sat 30 Mar 2019 | 41-2 v Oxford UnitedOxford United 2-1 Wycombe Wanderers | Sky Bet League One |
| 42 | Sat 6 Apr 2019 | 42-3 v PortsmouthWycombe Wanderers 2-3 Portsmouth | Sky Bet League One |
| 43 | Tue 9 Apr 2019 | 40-1 v Charlton AthleticWycombe Wanderers 0-1 Charlton Athletic | Sky Bet League One |
| 44 | Sat 13 Apr 2019 | 42-0 v Southend UnitedSouthend United 0-2 Wycombe Wanderers | Sky Bet League One |
| 45 | Fri 19 Apr 2019 | 40-1 v RochdaleRochdale 1-0 Wycombe Wanderers | Sky Bet League One |
| 46 | Mon 22 Apr 2019 | 41-0 v WalsallWycombe Wanderers 1-0 Walsall | Sky Bet League One |
| 47 | Sat 27 Apr 2019 | 41-2 v AFC WimbledonAFC Wimbledon 2-1 Wycombe Wanderers | Sky Bet League One |
| 48 | Sat 4 May 2019 | 41-0 v Fleetwood TownWycombe Wanderers 1-0 Fleetwood Town | Sky Bet League One |
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