| 1 | Thu 3 Dec 2020 | 300-0 v Red Star BelgradeRed Star Belgrade 0-0 1899 Hoffenheim | Europa League Group L |
| 2 | Thu 10 Dec 2020 | 30 4-1 v KAA Gent1899 Hoffenheim 4-1 KAA Gent | Europa League Group L |
| 3 | Sat 9 Jan 2021 | 300-4 v FC Schalke 04FC Schalke 04 4-0 1899 Hoffenheim | German Bundesliga |
| 4 | Sat 16 Jan 2021 | 30 0-0 v Arminia Bielefeld1899 Hoffenheim 0-0 Arminia Bielefeld | German Bundesliga |
| 5 | Tue 19 Jan 2021 | 303-0 v Hertha BerlinHertha Berlin 0-3 1899 Hoffenheim | German Bundesliga |
| 6 | Sun 24 Jan 2021 | 303-0 v 1. FC Köln1899 Hoffenheim 3-0 1. FC Köln | German Bundesliga |
| 7 | Sat 30 Jan 2021 | 301-4 v Bayern MunichBayern Munich 4-1 1899 Hoffenheim | German Bundesliga |
| 8 | Sun 7 Feb 2021 | 301-3 v Eintracht Frankfurt1899 Hoffenheim 1-3 Eintracht Frankfurt | German Bundesliga |
| 9 | Sat 13 Feb 2021 | 302-2 v Borussia DortmundBorussia Dortmund 2-2 1899 Hoffenheim | German Bundesliga |
| 10 | Thu 18 Feb 2021 | 303-3 v MoldeMolde 3-3 1899 Hoffenheim | Europa League Round of 32 |
| 11 | Sun 21 Feb 2021 | 304-0 v Werder Bremen1899 Hoffenheim 4-0 Werder Bremen | German Bundesliga |
| 12 | Thu 25 Feb 2021 | 300-2 v Molde1899 Hoffenheim 0-2 Molde | Europa League Round of 32 |
| 13 | Sun 28 Feb 2021 | 301-1 v 1. FC Union Berlin1. FC Union Berlin 1-1 1899 Hoffenheim | German Bundesliga |
| 14 | Sat 6 Mar 2021 | 302-1 v VfL Wolfsburg1899 Hoffenheim 2-1 VfL Wolfsburg | German Bundesliga |
| 15 | Sun 21 Mar 2021 | 301-2 v Mainz 051899 Hoffenheim 1-2 Mainz 05 | German Bundesliga |
| 16 | Sat 3 Apr 2021 | 301-2 v FC AugsburgFC Augsburg 2-1 1899 Hoffenheim | German Bundesliga |
| 17 | Sat 15 May 2021 | 301-1 v Arminia BielefeldArminia Bielefeld 1-1 1899 Hoffenheim | German Bundesliga |
| 18 | Sat 22 May 2021 | 302-1 v Hertha Berlin1899 Hoffenheim 2-1 Hertha Berlin | German Bundesliga |
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