| 1 | Thu 25 Jul | 221-0 v VojvodinaAjax 1-0 Vojvodina | UEFA Europa League Second Qualifying Round |
| 2 | Thu 1 Aug | 223-1 v VojvodinaVojvodina 1-3 Ajax | UEFA Europa League Second Qualifying Round |
| 3 | Thu 8 Aug | 221-0 v PanathinaikosPanathinaikos 0-1 Ajax | UEFA Europa League Third Qualifying Round |
| 4 | Sun 11 Aug | 221-0 v sc HeerenveenAjax 1-0 sc Heerenveen | Dutch Eredivisie |
| 5 | Thu 15 Aug | 220-1 v PanathinaikosAjax 0-1 Panathinaikos | UEFA Europa League Third Qualifying Round |
| 6 | Sun 18 Aug | 221-2 v NAC BredaNAC Breda 2-1 Ajax | Dutch Eredivisie |
| 7 | Thu 22 Aug | 224-1 v Jagiellonia BiałystokJagiellonia Białystok 1-4 Ajax | UEFA Europa League Play-off |
| 8 | Thu 29 Aug | 223-0 v Jagiellonia BiałystokAjax 3-0 Jagiellonia Białystok | UEFA Europa League Play-off |
| 9 | Wed 18 Sep | 225-0 v Fortuna SittardAjax 5-0 Fortuna Sittard | Dutch Eredivisie |
| 10 | Sat 21 Sep | 221-1 v Go Ahead EaglesGo Ahead Eagles 1-1 Ajax | Dutch Eredivisie |
| 11 | Thu 26 Sep | 224-0 v BeşiktaşAjax 4-0 Beşiktaş | UEFA Europa League Matchday 1 |
| 12 | Sun 29 Sep | 222-0 v RKC WaalwijkRKC Waalwijk 0-2 Ajax | Dutch Eredivisie |
| 13 | Thu 3 Oct | 221-1 v Slavia PragueSlavia Prague 1-1 Ajax | UEFA Europa League Matchday 2 |
| 14 | Sun 6 Oct | 223-1 v FC GroningenAjax 3-1 FC Groningen | Dutch Eredivisie |
| 15 | Sun 20 Oct | 224-3 v Heracles AlmeloHeracles Almelo 3-4 Ajax | Dutch Eredivisie |
| 16 | Thu 24 Oct | 223-0 v FK QarabağFK Qarabağ 0-3 Ajax | UEFA Europa League Matchday 3 |
| 17 | Wed 30 Oct | 222-0 v FeyenoordFeyenoord 0-2 Ajax | Dutch Eredivisie |
| 18 | Sat 2 Nov | 223-2 v PSV EindhovenAjax 3-2 PSV Eindhoven | Dutch Eredivisie |
| 19 | Thu 7 Nov | 225-0 v Maccabi Tel-AvivAjax 5-0 Maccabi Tel-Aviv | UEFA Europa League Matchday 4 |
| 20 | Sun 10 Nov | 222-2 v FC TwenteFC Twente 2-2 Ajax | Dutch Eredivisie |
| 21 | Sun 24 Nov | 222-0 v PEC ZwolleAjax 2-0 PEC Zwolle | Dutch Eredivisie |
| 22 | Thu 28 Nov | 220-2 v Real SociedadReal Sociedad 2-0 Ajax | UEFA Europa League Matchday 5 |
| 23 | Sun 1 Dec | 222-1 v NEC NijmegenNEC Nijmegen 1-2 Ajax | Dutch Eredivisie |
| 24 | Wed 4 Dec | 222-2 v FC UtrechtAjax 2-2 FC Utrecht | Dutch Eredivisie |
| 25 | Sun 8 Dec | 221-2 v AZ AlkmaarAZ Alkmaar 2-1 Ajax | Dutch Eredivisie |
| 26 | Thu 12 Dec | 221-3 v LazioAjax 1-3 Lazio | UEFA Europa League Matchday 6 |
| 27 | Sun 15 Dec | 223-0 v Almere CityAjax 3-0 Almere City | Dutch Eredivisie |
| 28 | Sun 22 Dec | 222-0 v Sparta RotterdamSparta Rotterdam 0-2 Ajax | Dutch Eredivisie |
| 29 | Sat 11 Jan | 222-1 v RKC WaalwijkAjax 2-1 RKC Waalwijk | Dutch Eredivisie |
| 30 | Sun 19 Jan | 222-0 v sc Heerenveensc Heerenveen 0-2 Ajax | Dutch Eredivisie |
| 31 | Thu 23 Jan | 220-1 v Rīgas FSRīgas FS 1-0 Ajax | UEFA Europa League Matchday 7 |
| 32 | Thu 30 Jan | 222-1 v GalatasarayAjax 2-1 Galatasaray | UEFA Europa League Matchday 8 |
| 33 | Sun 2 Feb | 222-1 v FeyenoordAjax 2-1 Feyenoord | Dutch Eredivisie |
| 34 | Sun 9 Feb | 222-0 v Fortuna SittardFortuna Sittard 0-2 Ajax | Dutch Eredivisie |
| 35 | Thu 13 Feb | 222-0 v Union Saint-GilloiseUnion Saint-Gilloise 0-2 Ajax | UEFA Europa League Play-off Knockout Round |
| 36 | Sun 16 Feb | 224-0 v Heracles AlmeloAjax 4-0 Heracles Almelo | Dutch Eredivisie |
| 37 | Thu 20 Feb | 221-2 v Union Saint-GilloiseAjax 1-2 Union Saint-Gilloise | UEFA Europa League Play-off Knockout Round |
| 38 | Sun 23 Feb | 222-0 v Go Ahead EaglesAjax 2-0 Go Ahead Eagles | Dutch Eredivisie |
| 39 | Thu 6 Mar | 221-2 v Eintracht FrankfurtAjax 1-2 Eintracht Frankfurt | UEFA Europa League Round of 16 |
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