| 1 | Sat 30 Sep | 143-1 v Leeds UnitedSouthampton 3-1 Leeds United | Sky Bet Championship |
| 2 | Wed 25 Oct | 142-2 v Preston North EndPreston North End 2-2 Southampton | Sky Bet Championship |
| 3 | Sat 28 Oct | 143-1 v Birmingham CitySouthampton 3-1 Birmingham City | Sky Bet Championship |
| 4 | Sat 4 Nov | 141-0 v MillwallMillwall 0-1 Southampton | Sky Bet Championship |
| 5 | Sat 11 Nov | 142-1 v West Bromwich AlbionSouthampton 2-1 West Bromwich Albion | Sky Bet Championship |
| 6 | Sat 25 Nov | 141-1 v Huddersfield TownHuddersfield Town 1-1 Southampton | Sky Bet Championship |
| 7 | Wed 29 Nov | 141-0 v Bristol CitySouthampton 1-0 Bristol City | Sky Bet Championship |
| 8 | Sat 9 Dec | 141-1 v WatfordWatford 1-1 Southampton | Sky Bet Championship |
| 9 | Sat 16 Dec | 144-0 v Blackburn RoversSouthampton 4-0 Blackburn Rovers | Sky Bet Championship |
| 10 | Sat 23 Dec | 141-0 v Queens Park RangersQueens Park Rangers 0-1 Southampton | Sky Bet Championship |
| 11 | Wed 28 Feb | 140-3 v LiverpoolLiverpool 3-0 Southampton | Emirates FA Cup Fifth Round |
| 12 | Sat 9 Mar | 144-2 v SunderlandSouthampton 4-2 Sunderland | Sky Bet Championship |
| 13 | Fri 29 Mar | 141-1 v MiddlesbroughSouthampton 1-1 Middlesbrough | Sky Bet Championship |
| 14 | Mon 1 Apr | 14 2-3 v Ipswich TownIpswich Town 3-2 Southampton | Sky Bet Championship |
| 15 | Tue 9 Apr | 142-1 v Coventry CitySouthampton 2-1 Coventry City | Sky Bet Championship |
| 16 | Sat 13 Apr | 143-2 v WatfordSouthampton 3-2 Watford | Sky Bet Championship |
| 17 | Sat 20 Apr | 141-2 v Cardiff CityCardiff City 2-1 Southampton | Sky Bet Championship |
| 18 | Tue 23 Apr | 140-5 v Leicester CityLeicester City 5-0 Southampton | Sky Bet Championship |
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