| 1 | Sat 7 Aug 2021 | 221-1 v Cardiff CityCardiff City 1-1 Barnsley | Sky Bet Championship |
| 2 | Sat 14 Aug 2021 | 221-0 v Coventry CityBarnsley 1-0 Coventry City | Sky Bet Championship |
| 3 | Tue 17 Aug 2021 | 220-1 v Luton TownBarnsley 0-1 Luton Town | Sky Bet Championship |
| 4 | Sat 21 Aug 2021 | 222-2 v Queens Park RangersQueens Park Rangers 2-2 Barnsley | Sky Bet Championship |
| 5 | Sat 28 Aug 2021 | 221-1 v Birmingham CityBarnsley 1-1 Birmingham City | Sky Bet Championship |
| 6 | Sat 11 Sep 2021 | 220-3 v AFC BournemouthAFC Bournemouth 3-0 Barnsley | Sky Bet Championship |
| 7 | Sat 18 Sep 2021 | 220-0 v Blackburn RoversBarnsley 0-0 Blackburn Rovers | Sky Bet Championship |
| 8 | Sat 25 Sep 2021 | 220-1 v BlackpoolBlackpool 1-0 Barnsley | Sky Bet Championship |
| 9 | Wed 29 Sep 2021 | 221-3 v Nottingham ForestBarnsley 1-3 Nottingham Forest | Sky Bet Championship |
| 10 | Sat 16 Oct 2021 | 220-1 v ReadingReading 1-0 Barnsley | Sky Bet Championship |
| 11 | Wed 20 Oct 2021 | 220-2 v MiddlesbroughMiddlesbrough 2-0 Barnsley | Sky Bet Championship |
| 12 | Sat 11 Dec 2021 | 221-2 v Preston North EndPreston North End 2-1 Barnsley | Sky Bet Championship |
| 13 | Fri 17 Dec 2021 | 220-0 v West Bromwich AlbionBarnsley 0-0 West Bromwich Albion | Sky Bet Championship |
| 14 | Wed 29 Dec 2021 | 221-2 v Blackburn RoversBlackburn Rovers 2-1 Barnsley | Sky Bet Championship |
| 15 | Sat 5 Mar 2022 | 220-2 v Derby CountyDerby County 2-0 Barnsley | Sky Bet Championship |
| 16 | Sat 12 Mar 2022 | 221-1 v FulhamBarnsley 1-1 Fulham | Sky Bet Championship |
| 17 | Tue 15 Mar 2022 | 222-0 v Bristol CityBarnsley 2-0 Bristol City | Sky Bet Championship |
| 18 | Sat 2 Apr 2022 | 221-1 v ReadingBarnsley 1-1 Reading | Sky Bet Championship |
| 19 | Sat 30 Apr 2022 | 221-3 v Preston North EndBarnsley 1-3 Preston North End | Sky Bet Championship |
| 20 | Sat 7 May 2022 | 220-4 v West Bromwich AlbionWest Bromwich Albion 4-0 Barnsley | Sky Bet Championship |
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