| 1 | Sat 17 Aug 2019 | 83-2 v SC Paderborn 07Bayer 04 Leverkusen 3-2 SC Paderborn 07 | German Bundesliga |
| 2 | Sat 24 Aug 2019 | 83-1 v Fortuna DüsseldorfFortuna Düsseldorf 1-3 Bayer 04 Leverkusen | German Bundesliga |
| 3 | Sat 31 Aug 2019 | 80-0 v 1899 HoffenheimBayer 04 Leverkusen 0-0 1899 Hoffenheim | German Bundesliga |
| 4 | Sat 14 Sep 2019 | 80-4 v Borussia DortmundBorussia Dortmund 4-0 Bayer 04 Leverkusen | German Bundesliga |
| 5 | Wed 18 Sep 2019 | 81-2 v Lokomotiv MoscowBayer 04 Leverkusen 1-2 Lokomotiv Moscow | UEFA Champions League Group D |
| 6 | Sat 21 Sep 2019 | 82-0 v 1. FC Union BerlinBayer 04 Leverkusen 2-0 1. FC Union Berlin | German Bundesliga |
| 7 | Tue 1 Oct 2019 | 80-3 v JuventusJuventus 3-0 Bayer 04 Leverkusen | UEFA Champions League Group D |
| 8 | Tue 22 Oct 2019 | 80-1 v Atlético MadridAtlético Madrid 1-0 Bayer 04 Leverkusen | UEFA Champions League Group D |
| 9 | Sat 26 Oct 2019 | 8 2-2 v Werder BremenBayer 04 Leverkusen 2-2 Werder Bremen | German Bundesliga |
| 10 | Sat 23 Nov 2019 | 81-1 v SC FreiburgBayer 04 Leverkusen 1-1 SC Freiburg | German Bundesliga |
| 11 | Tue 26 Nov 2019 | 82-0 v Lokomotiv MoscowLokomotiv Moscow 0-2 Bayer 04 Leverkusen | UEFA Champions League Group D |
| 12 | Sat 30 Nov 2019 | 82-1 v Bayern MunichBayern Munich 1-2 Bayer 04 Leverkusen | German Bundesliga |
| 13 | Sat 7 Dec 2019 | 82-1 v FC Schalke 04Bayer 04 Leverkusen 2-1 FC Schalke 04 | German Bundesliga |
| 14 | Wed 11 Dec 2019 | 80-2 v JuventusBayer 04 Leverkusen 0-2 Juventus | UEFA Champions League Group D |
| 15 | Sat 14 Dec 2019 | 80-2 v 1. FC Köln1. FC Köln 2-0 Bayer 04 Leverkusen | German Bundesliga |
| 16 | Wed 18 Dec 2019 | 80-1 v Hertha BerlinBayer 04 Leverkusen 0-1 Hertha Berlin | German Bundesliga |
| 17 | Sun 19 Jan 2020 | 84-1 v SC Paderborn 07SC Paderborn 07 1-4 Bayer 04 Leverkusen | German Bundesliga |
| 18 | Sun 26 Jan 2020 | 83-0 v Fortuna DüsseldorfBayer 04 Leverkusen 3-0 Fortuna Düsseldorf | German Bundesliga |
| 19 | Sat 1 Feb 2020 | 8 1-2 v 1899 Hoffenheim1899 Hoffenheim 2-1 Bayer 04 Leverkusen | German Bundesliga |
| 20 | Sat 15 Feb 2020 | 83-2 v 1. FC Union Berlin1. FC Union Berlin 2-3 Bayer 04 Leverkusen | German Bundesliga |
| 21 | Thu 20 Feb 2020 | 82-1 v FC PortoBayer 04 Leverkusen 2-1 FC Porto | Europa League Round of 32 |
| 22 | Thu 27 Feb 2020 | 8 3-1 v FC PortoFC Porto 1-3 Bayer 04 Leverkusen | Europa League Round of 32 |
| 23 | Sat 27 Jun 2020 | 81-0 v Mainz 05Bayer 04 Leverkusen 1-0 Mainz 05 | German Bundesliga |
| 24 | Mon 10 Aug 2020 | 8 1-2 v Inter MilanInter Milan 2-1 Bayer 04 Leverkusen | Europa League Quarter Final |
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